Evidence map›Paper›PMID 31711529›Full record

ArticleJournal of ovarian research2019

Long-term multidisciplinary integrative therapy management resulted in favorable outcomes for ovarian cancer during pregnancy: a case report and literature review.

Tianmin Xu, Liang Wang, Yan Jia, Zanhui Jia, Zhuo Li, Shaohai Cui, Manhua Cui

Open access · goldAbstract readCase Reports
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of ovarian research, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
0.8field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 12 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Tianmin XuDepartment of Gynecology and Obstetrics, the Second Hospital of Jilin University, Changchun, 130041, Jilin, China.
Liang WangDepartment of Gynecology and Obstetrics, the Second Hospital of Jilin University, Changchun, 130041, Jilin, China.ORCID http://orcid.org/0000-0003-0263-4309
Yan JiaDepartment of Gynecology and Obstetrics, the Second Hospital of Jilin University, Changchun, 130041, Jilin, China.
Zanhui JiaDepartment of Gynecology and Obstetrics, the Second Hospital of Jilin University, Changchun, 130041, Jilin, China.
Zhuo LiDepartment of Gynecology and Obstetrics, the Second Hospital of Jilin University, Changchun, 130041, Jilin, China.
Shaohai CuiDepartment of Gynecology and Obstetrics, the Second Hospital of Jilin University, Changchun, 130041, Jilin, China.
Manhua CuiDepartment of Gynecology and Obstetrics, the Second Hospital of Jilin University, Changchun, 130041, Jilin, China. cuimanhua@126.com.
Second Affiliated Hospital of Jilin University · CN

Funding

Department of Science and Technology of Jilin Province 20170622008JC
6 · The paper itself

Abstract

backgroundOvarian cancer during pregnancy is relatively rare and treatment strategies are inexperienced in surgery and chemotherapy. Multidisciplinary management of advanced epithelial ovarian cancer in pregnant patients with strong desire of fertility including sufficient mental and medical understanding, perioperative consideration, intraoperative decision, chemotherapy sensitivity and follow-up after treatment can gain successful outcomes for both maternal disease and fetus's development. CASE PRESENTATION: A 34-year-old primigravidae was diagnosed with advanced epithelial ovarian tumor and then first cytoreductive surgery to resect macroscopical lesions and protect the uterus for fetus was performed following with four chemotherapy courses (docetaxel and carboplatin) before delivery and four other chemotherapy courses after delivery. Chemotherapy drugs were decided by sensitivity test and the patient's anaphylaxis. Second surgery involved cesarean section with a healthy offspring and secondary cytoreductive surgery. Operative strategies were considered to gain a balance of disease and risk for fetus. Psychosocial support was provided during the course of diagnosis and treatment for a healthy coping situation. This patient relapsed 19 months after the last chemotherapy course and was treated by additional adjuvant therapy to a clinical remission. The 33-month baby boy has no evidence with disease until now. The follow-up of both mother and baby is still continuing.

conclusionsOvarian cancer during pregnancy has low incidence which must increase in future as women delay reproduction age. Ovarian cancer cytoreductive surgery and chemotherapy have limitation to handle conditions under a desire of fetus protection. Multidisciplinary treatment model is a therapeutic solution and a challenge for gynecological surgeons, medical oncologists, pathologists, obstetricians, neonatologists, pharmacists, anesthetist, and psychologists.

Indexed as

AdultAntineoplastic AgentsCarboplatinCarcinoma, Ovarian EpithelialChemotherapy, AdjuvantCombined Modality TherapyCytoreduction Surgical ProceduresDocetaxelFemaleHumansOvarian NeoplasmsPregnancyPregnancy ComplicationsTreatment OutcomeAntineoplastic AgentsCarboplatinDocetaxelChemotherapyComprehensive treatmentDebulking surgeryOvarian cancerPregnancy

Identifiers

PMID31711529
PMCPMC6844043
OpenAlexW2982715116

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.