Evidence map›Paper›PMID 31711443›Full record

ArticleBMC ophthalmology2019

Iridocorneal endothelial syndrome in a patient with keratoconus - a case report.

Michele De Maria, Danilo Iannetta, Antonio Moramarco, Luigi Fontana

Open access · goldAbstract readCase Reports
In one paragraph

Article in BMC ophthalmology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.5field-weighted citation impact, top 30% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 8 citations in OpenAlex.

  1. Unilateral keratoconus associated with iridocorneal endothelial syndrome: Case report.Saudi journal of ophthalmology : official journal of the Saudi Ophthalmological Society
    Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Michele De MariaOphthalmology Unit, AUSL-IRCCS of Reggio Emilia, Reggio Emilia, Italy.
Danilo IannettaOphthalmology Unit, AUSL-IRCCS of Reggio Emilia, Reggio Emilia, Italy.
Antonio MoramarcoOphthalmology Unit, AUSL-IRCCS of Reggio Emilia, Reggio Emilia, Italy.
Luigi FontanaOphthalmology Unit, AUSL-IRCCS of Reggio Emilia, Reggio Emilia, Italy. luifonta@gmail.com.ORCID http://orcid.org/0000-0003-3877-0417
Azienda Sanitaria Unità Locale di Reggio Emilia · ITUniversity of Modena and Reggio Emilia · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundTo describe a case of a rare association of bilateral keratoconus and unilateral essential iris atrophy and to conduct a literature review of the current strategies of treatment of the corneal disease and glaucoma in patients with Iridocorneal Endothelial Syndrome (ICE). CASE PRESENTATION: We report a rare association of bilateral keratoconus and unilateral essential iris atrophy in a 38-year-old man. Diagnosis of bilateral keratoconus was confirmed by corneal topography. Slit-lamp examination showed extensive iris atrophy with corectopia and policoria in one eye. Corneal specular microscopy revealed an abnormal endothelium morphology in the same eye with extensive peripheral anterior synechiae and closure of the drainage angle at gonioscopy. Intraocular pressure was 26 mmHg, despite maximal topical therapy. Optic disc examination showed severe glaucomatous cupping. Surgery by glaucoma drainage device implantation was performed.

conclusionEssential iris atrophy is a rare clinical variant of ICE syndrome characterized by profound anatomical alterations of the anterior segment associated with corneal edema and secondary glaucoma. In these patients, selective keratoplasties have replaced penetrating keratoplasty to treat corneal decompensation and glaucoma drainage devices are preferred to conventional trabeculectomy for the treatment of secondary glaucoma.

Indexed as

AdultAtrophyHumansIridocorneal Endothelial SyndromeIris DiseasesKeratoconusMaleEssential iris atrophyGlaucomaIridocorneal endothelial syndromeKeratoconusKeratoplasty

Identifiers

PMID31711443
PMCPMC6849214
OpenAlexW2989446120

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.