Evidence map›Paper›PMID 31711422›Full record

Trial reportBMC anesthesiology2019

Hypoxia preconditioning attenuates lung injury after thoracoscopic lobectomy in patients with lung cancer: a prospective randomized controlled trial.

Wenjing Zhang, Mo Chen, Hongbin Li, Jia Yuan, Jingjing Li, Feixiang Wu, Yan Zhang

Open access · goldAbstract readRandomized Controlled Trial
PubMed Full text at PMC Publisher
In one paragraph

Trial report in BMC anesthesiology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed, 1 pooled it
1.7field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 1 synthesis or guideline pooled it, 15 citations in OpenAlex.

  1. Pooled it
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  12. Remote ischemic conditioning for acute respiratory distress syndrome in COVID-19.American journal of physiology. Lung cellular and molecular physiology · 2021
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 1 country.

Wenjing ZhangDepartment of Anesthesiology, Zhoushan Hospital, No.739 Dingshen Street, Zhoushan, Zhejiang, China.
Mo ChenDepartment of Anesthesiology, Suzhou Municipal Hospital (North District), Nanjing Medical University Affiliated Suzhou Hospital, No.242 Guangji Road, Suzhou, Jiangsu, China.
Hongbin LiDepartment of Anesthesiology, Zhoushan Hospital, No.739 Dingshen Street, Zhoushan, Zhejiang, China.
Jia YuanDepartment of Anesthesiology, Zhoushan Hospital, No.739 Dingshen Street, Zhoushan, Zhejiang, China.
Jingjing LiDepartment of Anesthesiology, Zhoushan Hospital, No.739 Dingshen Street, Zhoushan, Zhejiang, China.
Feixiang WuDepartment of Anesthesiology, Shanghai Eastern Hepatobiliary Surgery Hospital, Second Military Medical University, No.225 Changhai Road, Shanghai, China. feixiangwu@hotmail.com.
Yan ZhangDepartment of Anesthesiology, Zhoushan Hospital, No.739 Dingshen Street, Zhoushan, Zhejiang, China. zy476291@163.com.ORCID 0000-0001-9688-7221
Zhoushan Hospital · CNSecond Military Medical University · CNSuzhou Municipal Hospital · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundHypoxic preconditioning (HPC) may protect multiple organs from various injuries. We hypothesized that HPC would reduce lung injury in patients undergoing thoracoscopic lobectomy.

methodsIn a prospective randomized controlled trial, 70 patients undergoing elective thoracoscopic lobectomy were randomly allocated to the HPC group or the control group. Three cycles of 5-min hypoxia and 3-min ventilation applied to the nondependent lung served as the HPC intervention. The primary outcome was the PaO

resultsHPC significantly increased the PaO

conclusionsHPC improves postoperative oxygenation, enhances the recovery of pulmonary function, and reduces the duration of hospital stay in patients undergoing thoracoscopic lobectomy.

trial registrationThis study was registered in the Chinese Clinical Trial Registry (ChiCTR-IPR-17011249) on April 27, 2017.

Indexed as

AgedCarcinoma, Non-Small-Cell LungFemaleHumansHypoxiaLength of StayLung InjuryLung NeoplasmsMaleMiddle AgedOne-Lung VentilationPneumonectomyPostoperative ComplicationsProspective StudiesThoracoscopyHypoxic preconditioningNon-small cell lung cancerOne-lung ventilationPaO2/FiO2 ratioPulmonary complicationsThoracoscopic lobectomy

Identifiers

PMID31711422
PMCPMC6849275
OpenAlexW2984333532

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.