Evidence map›Paper›PMID 31711335›Full record

ArticleInnate immunity2020

Characterization of the NLRP1 inflammasome response in bovine species.

Catherine E Vrentas, Paola M Boggiatto, Steven C Olsen, Stephen H Leppla, Mahtab Moayeri

Abstract read
In one paragraph

Article in Innate immunity, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. A Comprehensive Review of the Bovine Immune Response to Pathogens.International journal of molecular sciences · 2025
    Review
  2. mInternational journal of molecular sciences · 2025
    Article
  3. Review
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Catherine E VrentasInfectious Bacterial Diseases Unit, National Animal Disease Center, Agricultural Research Service, US Department of Agriculture, Ames, USA.ORCID 0000-0003-1434-654X
Paola M BoggiattoInfectious Bacterial Diseases Unit, National Animal Disease Center, Agricultural Research Service, US Department of Agriculture, Ames, USA.
Steven C OlsenInfectious Bacterial Diseases Unit, National Animal Disease Center, Agricultural Research Service, US Department of Agriculture, Ames, USA.
Stephen H LepplaLaboratory of Parasitic Diseases, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, USA.ORCID 0000-0001-5233-0501
Mahtab MoayeriLaboratory of Parasitic Diseases, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, USA.

Funding

Pathophysiological Actions of the Anthrax ToxinsZIAAI001032 · NIAID · NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEASES · PI LEPPLA, STEPHEN · 2009 to 2025
$10.9M
6 · The paper itself

Abstract

Inflammasomes act as sensors of infection or damage to initiate immune responses. While extensively studied in rodents, understanding of livestock inflammasomes is limited. The NLRP1 inflammasome sensor in rodents is activated by

Indexed as

AnimalsAnthraxAntigens, BacterialApoptosisBacillus anthracisBacterial ToxinsBisonCaspase 1CattleCells, CulturedImmunity, InnateInflammasomesMacrophagesNLR ProteinsProteolysisSpecies Specificityanthrax toxinAntigens, BacterialBacterial ToxinsCaspase 1InflammasomesNLR ProteinsBisonbovineinflammasomelethal toxinNLRP1

Identifiers

PMID31711335
PMCPMC7251794

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.