ArticleThe Journal of antimicrobial chemotherapy2020
Faecal carriage, risk factors, acquisition and persistence of ESBL-producing Enterobacteriaceae in dogs and cats and co-carriage with humans belonging to the same household.
Article in The Journal of antimicrobial chemotherapy, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 59 papers.
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Who cites it
59 citing papers in PubMed, 86 citations in OpenAlex.
- Extended-Spectrum β-Lactamase-ProducingAnimals : an open access journal from MDPI · 2026Article
- Phenotypic and Genetic Profile, Biofilm-Forming Ability and Antibiotic Sensibility of ESBL-ProducingAntibiotics (Basel, Switzerland) · 2026Article
- Article
- Metagenomic analysis of antimicrobial resistance genes in domestic canines.One health (Amsterdam, Netherlands) · 2026Article
- Role of Households with Children in Community Spread of Multidrug-Resistant Enterobacterales, St. Louis, Missouri, USA.Emerging infectious diseases · 2026Article
- Genomic insights into multidrug resistance and virulence of methicillin-resistantFrontiers in veterinary science · 2026Article
- Companion Animals Harbour Globally Circulating Human-Associated Klebsiella pneumoniae Lineages and High-Risk Antimicrobial Resistance Clones.Transboundary and emerging diseases · 2026Article
- Molecular characterization of ESBL- and carbapenemase-producing Enterobacteriaceae isolated from cats in Lebanon.BMC microbiology · 2025Article
- Urinary tract infection in a cat and cholangiohepatitis in a dog caused by the same strain of CTX-M-14 extended-spectrum beta-lactamase-producingASM case reports · 2025Article
- OXA-244-producing Escherichia coli isolated from a dog in Portugal.Veterinary research communications · 2025Article
- Extended Spectrum Beta-Lactamase Producing Escherichia coli in Pet Cats and Dogs in Central Peninsular Malaysia.Veterinary medicine and science · 2025Article
- Genomic epidemiology of third-generation cephalosporin-resistantOne health (Amsterdam, Netherlands) · 2025Article
- The Risk Factors Associated with the Carriage to Critical Antimicrobial-ResistantAnimals : an open access journal from MDPI · 2025Article
- Companions in antimicrobial resistance: examining transmission of common antimicrobial-resistant organisms between people and their dogs, cats, and horses.Clinical microbiology reviews · 2025Review
- Threats across boundaries: the spread of ESBL-positiveFrontiers in microbiology · 2025Review
- Canine Multidrug-Resistant Pseudomonas aeruginosa Cases Linked to Human Artificial Tears-Related Outbreak.Emerging infectious diseases · 2024Article
- Colonization with resistant bacteria in hospital employees: an epidemiological surveillance and typing study.Antimicrobial agents and chemotherapy · 2024Article
- Prevalence and antimicrobial resistance of Enterobacteriaceae in the north of Kazakhstan.Open veterinary journal · 2024Article
- Multidrug resistance in pathogenicFrontiers in veterinary science · 2024Article
- Zoonoses in dog and cat shelters in North-East Italy: update on emerging, neglected and known zoonotic agents.Frontiers in veterinary science · 2024Article
Corrections and comments
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Authors and funding
12 authors at 4 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundESBL-producing Enterobacteriaceae (ESBL-E) are observed in many reservoirs. Pets might play an important role in the dissemination of ESBL-E to humans since they live closely together.
objectivesTo identify prevalence, risk factors, molecular characteristics, persistence and acquisition of ESBL-E in dogs and cats, and co-carriage in human-pet pairs belonging to the same household.
methodsIn a nationwide study, one person per household was randomly invited to complete a questionnaire and to submit a faecal sample. Dog and cat owners were invited to also submit a faecal sample from their pet. Repeated sampling after 1 and 6 months was performed in a subset. ESBL-E were obtained through selective culture and characterized by WGS. Logistic regression analyses and random forest models were performed to identify risk factors.
resultsThe prevalence of ESBL-E carriage in these cohorts was 3.8% (95% CI: 2.7%-5.4%) for human participants (n=550), 10.7% (95% CI: 8.3%-13.7%) for dogs (n=555) and 1.4% (95% CI: 0.5%-3.8%) for cats (n=285). Among animals, blaCTX-M-1 was most abundant, followed by blaCTX-M-15. In dogs, persistence of carriage was 57.1% at 1 month and 42.9% at 6 months. Eating raw meat [OR: 8.8, 95% CI: 4.7-16.4; population attributable risk (PAR): 46.5%, 95% CI: 41.3%-49.3%] and dry food (OR: 0.2, 95% CI: 0.1-0.5; PAR: 56.5%, 95% CI: 33.2%-66.6%) were predictors for ESBL-E carriage in dogs. Human-dog co-carriage was demonstrated in five households. Human-cat co-carriage was not observed.
conclusionsESBL-E prevalence was higher in dogs than in humans and lowest in cats. The main risk factor for ESBL-E carriage was eating raw meat. Co-carriage in dogs and household members was uncommon.
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