Evidence map›Paper›PMID 31710876›Full record

ArticleSleep medicine2020

Depression and suicidal ideation in pregnancy: exploring relationships with insomnia, short sleep, and nocturnal rumination.

David A Kalmbach, Philip Cheng, Jason C Ong, Jeffrey A Ciesla, Sheryl A Kingsberg, Roopina Sangha, Leslie M Swanson, Louise M O'Brien, Thomas Roth, Christopher L Drake

Registry-linked trialOpen access · greenAbstract read
In one paragraph

Article in Sleep medicine, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT03596879 (Insomnia and Rumination in Late-pregnancy and the Risk for Postpartum Depression), which is not on this map. Cited by 52 papers, 6 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
52citing papers in PubMed, 6 pooled it
9.5field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT03596879 nacompletednot on this map

Insomnia and Rumination in Late-pregnancy and the Risk for Postpartum Depression (PPD): A Randomized Controlled Trial of Online Cognitive Behavioral Therapy for Insomnia to Prevent PPD

TypeinterventionalSponsorHenry Ford Health SystemRan2018 to 2019Enrolled91ConditionsInsomnia, Post Partum DepressionArmsdCBTI, Sleep Education
3 · Its place in the literature

Who cites it

52 citing papers in PubMed, 6 syntheses or guidelines pooled it, 97 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 6 institutions in 1 country.

David A KalmbachThomas Roth Sleep Disorders & Research Center, Division of Sleep Medicine, Henry Ford Health System, Detroit, MI, 48202, USA. Electronic address: dkalmba1@hfhs.org.
Philip ChengThomas Roth Sleep Disorders & Research Center, Division of Sleep Medicine, Henry Ford Health System, Detroit, MI, 48202, USA.
Jason C OngDepartments of Neurology and Psychiatry & Behavioral Sciences, Feinberg School of Medicine, Northwestern University, Chicago, IL, 60611, USA.
Jeffrey A CieslaDepartment of Psychological Sciences, Kent State University, Kent, OH, 44240, USA.
Sheryl A KingsbergDepartments of Reproductive Biology and Psychiatry, Case Western Reserve University, Cleveland, OH, 44106, USA.
Roopina SanghaDepartment of Obstetrics & Gynecology, Henry Ford Health System, Detroit, MI, 48202, USA.
Leslie M SwansonDepartment of Psychiatry, University of Michigan, Ann Arbor, MI, 48109, USA.
Louise M O'BrienDepartments of Obstetrics & Gynecology and Neurology, Ann Arbor, MI, 48105, USA.
Thomas RothThomas Roth Sleep Disorders & Research Center, Division of Sleep Medicine, Henry Ford Health System, Detroit, MI, 48202, USA.
Christopher L DrakeThomas Roth Sleep Disorders & Research Center, Division of Sleep Medicine, Henry Ford Health System, Detroit, MI, 48202, USA.
Henry Ford Health System · USCase Western Reserve University · USKent State University · USMichigan Medicine · USNorthwestern University · USUniversity of Michigan · US

Funding

Sleep-Disordered Breathing and PAP in Perinatal DepressionK23HL122461 · NHLBI · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI SWANSON, LESLIE M · 2015 to 2019
$813k
Clinical translation of phenotypes of shift work disorderK23HL138166 · NHLBI · HENRY FORD HEALTH SYSTEM · PI CHENG, PHILIP · 2017 to 2021
$761k
NHLBI NIH HHS K23 HL122461NHLBI NIH HHS K23 HL138166
6 · The paper itself

Abstract

backgroundSleep problems and depression are highly prevalent in pregnancy. Nocturnal rumination has been linked to insomnia and depression in non-pregnant samples, but remains poorly characterized in pregnancy. This study explored relationships of depression and suicidal ideation with insomnia, short sleep, and nocturnal rumination in mid-to-late pregnancy.

methodsIn this study, 267 pregnant women were recruited from obstetric clinics and completed online surveys on sleep, depression, and nocturnal rumination.

resultsOver half (58.4%) of the sample reported clinical insomnia on the Insomnia Severity Index, 16.1% screened positive for major depression on the Edinburgh Postnatal Depression Scale (EPDS), and 10.1% endorsed suicidal ideation. Nocturnal rumination was more robustly associated with sleep onset difficulties than with sleep maintenance issues. Depressed women were at greater odds of sleep onset insomnia (OR = 2.80), sleep maintenance insomnia (OR = 6.50), high nocturnal rumination (OR = 6.50), and negative perinatal-focused rumination (OR = 2.70). Suicidal ideation was associated with depression (OR = 3.64) and negative perinatal-focused rumination (OR = 3.50). A four-group comparison based on insomnia status and high/low rumination revealed that pregnant women with insomnia and high rumination endorsed higher rates of depression (35.6%) and suicidal ideation (17.3%) than good-sleeping women with low rumination (1.2% depressed, 4.9% suicidal). Women with insomnia alone (depression: 3.9%, suicidal: 5.9%) or high rumination alone (depression: 10.7%, suicidal: 7.1%) did not differ from good-sleeping women with low rumination.

conclusionsHigh rumination and insomnia are highly common in mid-to-late pregnancy and both are associated with depression and suicidal ideation. Depression and suicidal ideation are most prevalent in pregnant women with both insomnia and high rumination. CLINICALTRIALS. GOV IDENTIFIER: NCT03596879.

Indexed as

Suicidal IdeationAdultFemaleHumansMajor Depressive DisorderPregnancyPregnant PeoplePrevalencePsychiatric Status Rating ScalesSleep Initiation and Maintenance DisordersSurveys and QuestionnairesCognitive arousalPerinatalPrenatalPre-sleep arousalStressSuicidality

Identifiers

PMID31710876
PMCPMC6980654
OpenAlexW2964124853

What OpenQuestion holds

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.