Evidence map›Paper›PMID 31710859›Full record

Trial reportGeneral hospital psychiatry

Positive screening rates for bipolar disorder in pregnant and postpartum women and associated risk factors.

Grace A Masters, Linda Brenckle, Padma Sankaran, Sharina D Person, Jeroan Allison, Tiffany A Moore Simas, Jean Y Ko, Cheryl L Robbins, Wendy Marsh, Nancy Byatt

Registry-linked trialAbstract readRandomized Controlled Trial
In one paragraph

Trial report in General hospital psychiatry. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT02760004 (PRogram In Support of Moms), which is not on this map. Cited by 12 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT02760004 nacompletednot on this map

PRogram In Support of Moms: An Innovative Stepped-Care Approach for Obstetrics and Gynecology Clinics

TypeinterventionalSponsorUniversity of Massachusetts, WorcesterRan2017 to 2022Enrolled312ConditionsDepressionArmsPRogram In Support of Moms (PRISM), MCPAP for Moms
3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 2 syntheses or guidelines pooled it.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Grace A MastersUniversity of Massachusetts Medical School, 55 Lake Avenue, Worcester, MA 01655, United States of America. Electronic address: Grace.Masters@UMassMed.edu.
Linda BrenckleUniversity of Massachusetts Medical School, 55 Lake Avenue, Worcester, MA 01655, United States of America. Electronic address: Linda.Brenckle@UMassMed.edu.
Padma SankaranUniversity of Massachusetts Medical School, 55 Lake Avenue, Worcester, MA 01655, United States of America. Electronic address: Padma.Sankaran@UMassMed.edu.
Sharina D PersonUniversity of Massachusetts Medical School, 55 Lake Avenue, Worcester, MA 01655, United States of America. Electronic address: Sharina.Person@UMassMed.edu.
Jeroan AllisonUniversity of Massachusetts Medical School, 55 Lake Avenue, Worcester, MA 01655, United States of America. Electronic address: Jeroan.Allison@UMassMed.edu.
Tiffany A Moore SimasUniversity of Massachusetts Medical School, 55 Lake Avenue, Worcester, MA 01655, United States of America; UMass Memorial Health Care, Worcester, MA, United States of America. Electronic address: TiffanyA.MooreSimas@UMassMemorial.org.
Jean Y KoCenters for Disease Control and Prevention, Atlanta, GA, United States of America; U.S. Public Health Service Commissioned Corps, Rockville, MD, United States of America. Electronic address: fob1@cdc.gov.
Cheryl L RobbinsCenters for Disease Control and Prevention, Atlanta, GA, United States of America. Electronic address: ggf9@cdc.gov.
Wendy MarshUniversity of Massachusetts Medical School, 55 Lake Avenue, Worcester, MA 01655, United States of America; UMass Memorial Health Care, Worcester, MA, United States of America. Electronic address: Wendy.Marsh@UmassMemorial.org.
Nancy ByattUniversity of Massachusetts Medical School, 55 Lake Avenue, Worcester, MA 01655, United States of America; UMass Memorial Health Care, Worcester, MA, United States of America. Electronic address: Nancy.Byatt@UMassMemorial.org.

Funding

University of Massachusetts Center for Clinical Science and Translational SupplementUL1TR001453 · NCATS · UNIV OF MASSACHUSETTS MED SCH WORCESTER · PI LUZURIAGA, KATHERINE F · 2015 to 2024
$39.0M
University of Massachusetts Center for Clinical and Translational ScienceUL1TR000161 · NCATS · UNIV OF MASSACHUSETTS MED SCH WORCESTER · PI LUZURIAGA, KATHERINE F · 2012 to 2015
$11.0M
University of Massachusetts Center for Clinical and Translational ScienceKL2TR001455 · NCATS · UNIV OF MASSACHUSETTS MED SCH WORCESTER · PI KIEFE, CATARINA I. · 2015 to 2024
$5.0M
University of Massachusetts Center for Clinical and Translational ScienceTL1TR001454 · NCATS · UNIV OF MASSACHUSETTS MED SCH WORCESTER · PI LEWIS, BRIAN C · 2015 to 2024
$3.6M
Rapid Access to Perinatal Psychiatric Care in Depression Program (RAPPID): An Innovative Stepped-Care Approach for Obstetrics and Gynecology ClinicsU01DP006093 · DP · UNIV OF MASSACHUSETTS MED SCH WORCESTER · PI BYATT, NANCY, MOORE SIMAS, TIFFANY ANNE · 2015 to 2019
$2.6M
University of Massachusetts Center for Clinical and Translational ScienceKL2TR000160 · NCATS · UNIV OF MASSACHUSETTS MED SCH WORCESTER · PI LUZURIAGA, KATHERINE F · 2012 to 2014
$1.7M
Online Training For Addressing Perinatal DepressionR41MH113381 · NIMH · PRAXIS, INC. · PI BYATT, NANCY · 2017 to 2017
$224k
ACL HHS U01DP006093Intramural CDC HHS CC999999NCATS NIH HHS KL2 TR000160NCATS NIH HHS KL2 TR001455NCATS NIH HHS TL1 TR001454NCATS NIH HHS UL1 TR000161NCATS NIH HHS UL1 TR001453NCCDPHP CDC HHS U01 DP006093NIMH NIH HHS R41 MH113381
6 · The paper itself

Abstract

objectiveBipolar disorder affects 2-8% of pregnant and postpartum women; untreated illness is associated with poor outcomes. This study aimed to describe bipolar disorder screening rates in obstetric settings and associated characteristics.

methodWomen were recruited during pregnancy through three months postpartum from 14 obstetric clinics in Massachusetts. The Mood Disorder Questionnaire (MDQ) was used to screen for bipolar disorder; a subset previously diagnosed with bipolar was also examined. Differences in characteristics by screening outcome were tested using chi-square and t-tests.

resultsOf 574 participating women, 18.8% screened positive for bipolar disorder. Compared to those with negative, those with positive bipolar screens had 18.5-times the prevalence of positive substance use screens (11.1% vs. 0.6%, p < 0.001) and 3.4-times reported feeling they were not receiving adequate psychiatric help (24.0 vs. 7.0%, p < 0.001). Less than half of those with positive bipolar screens (42.0%) and 61.3% with pre-existing bipolar reported receiving current psychiatric care.

conclusionsAlmost one in five perinatal women screened positive for bipolar disorder. Positive screenings were associated with comorbid substance use and low treatment rates. This study highlights the importance of screening for bipolar disorder during the perinatal period and the need for systematic approaches to ensure adequate assessment and follow-up. CLINICAL TRIALS REGISTRATION: ClinicalTrials.gov identifier: NCT02760004.

Indexed as

AdolescentAdultBipolar DisorderFemaleHospitals, MaternityHumansLongitudinal StudiesMassachusettsMiddle AgedPregnancyPregnancy ComplicationsPuerperal DisordersYoung AdultBipolar disorderMood Disorder QuestionnairePerinatal

Identifiers

PMID31710859
PMCPMC6932868

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.