Evidence map›Paper›PMID 31710713›Full record

ReviewBritish journal of pharmacology2019

THE CONCISE GUIDE TO PHARMACOLOGY 2019/20: Transporters.

Stephen P H Alexander, Eamonn Kelly, Alistair Mathie, John A Peters, Emma L Veale, Jane F Armstrong, Elena Faccenda, Simon D Harding, Adam J Pawson, Joanna L Sharman and 3 more

Abstract readReview
In one paragraph

Review in British journal of pharmacology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 116 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
116citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

116 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Trial
  3. Trial
  4. Trial
  5. Trial
  6. Article
  7. The evolving landscape of drug targets.Nature reviews. Drug discovery · 2026
    Review
  8. Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. Review
  15. Article
  16. Article
  17. Review
  18. Article
  19. Article
  20. Article

56 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Stephen P H AlexanderSchool of Life Sciences, University of Nottingham Medical School, Nottingham, NG7 2UH, UK.ORCID 0000-0003-4417-497X
Eamonn KellySchool of Physiology, Pharmacology and Neuroscience, University of Bristol, Bristol, BS8 1TD, UK.
Alistair MathieMedway School of Pharmacy, The Universities of Greenwich and Kent at Medway, Anson Building, Central Avenue, Chatham Maritime, Chatham, Kent, ME4 4TB, UK.ORCID 0000-0001-6094-2890
John A PetersNeuroscience Division, Medical Education Institute, Ninewells Hospital and Medical School, University of Dundee, Dundee, DD1 9SY, UK.ORCID 0000-0002-4277-4245
Emma L VealeMedway School of Pharmacy, The Universities of Greenwich and Kent at Medway, Anson Building, Central Avenue, Chatham Maritime, Chatham, Kent, ME4 4TB, UK.ORCID 0000-0002-6778-9929
Jane F ArmstrongCentre for Discovery Brain Sciences, University of Edinburgh, Edinburgh, EH8 9XD, UK.ORCID 0000-0002-0524-0260
Elena FaccendaCentre for Discovery Brain Sciences, University of Edinburgh, Edinburgh, EH8 9XD, UK.ORCID 0000-0001-9855-7103
Simon D HardingCentre for Discovery Brain Sciences, University of Edinburgh, Edinburgh, EH8 9XD, UK.ORCID 0000-0002-9262-8318
Adam J PawsonCentre for Discovery Brain Sciences, University of Edinburgh, Edinburgh, EH8 9XD, UK.ORCID 0000-0003-2280-845X
Joanna L SharmanCentre for Discovery Brain Sciences, University of Edinburgh, Edinburgh, EH8 9XD, UK.ORCID 0000-0002-5275-6446
Christopher SouthanCentre for Discovery Brain Sciences, University of Edinburgh, Edinburgh, EH8 9XD, UK.ORCID 0000-0001-9580-0446
Jamie A DaviesCentre for Discovery Brain Sciences, University of Edinburgh, Edinburgh, EH8 9XD, UK.ORCID 0000-0001-6660-4032
CGTP Collaborators

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The Concise Guide to PHARMACOLOGY 2019/20 is the fourth in this series of biennial publications. The Concise Guide provides concise overviews of the key properties of nearly 1800 human drug targets with an emphasis on selective pharmacology (where available), plus links to the open access knowledgebase source of drug targets and their ligands (www.guidetopharmacology.org), which provides more detailed views of target and ligand properties. Although the Concise Guide represents approximately 400 pages, the material presented is substantially reduced compared to information and links presented on the website. It provides a permanent, citable, point-in-time record that will survive database updates. The full contents of this section can be found at http://onlinelibrary.wiley.com/doi/10.1111/bph.14753. Transporters are one of the six major pharmacological targets into which the Guide is divided, with the others being: G protein-coupled receptors, ion channels, nuclear hormone receptors, catalytic receptors and enzymes. These are presented with nomenclature guidance and summary information on the best available pharmacological tools, alongside key references and suggestions for further reading. The landscape format of the Concise Guide is designed to facilitate comparison of related targets from material contemporary to mid-2019, and supersedes data presented in the 2017/18, 2015/16 and 2013/14 Concise Guides and previous Guides to Receptors and Channels. It is produced in close conjunction with the International Union of Basic and Clinical Pharmacology Committee on Receptor Nomenclature and Drug Classification (NC-IUPHAR), therefore, providing official IUPHAR classification and nomenclature for human drug targets, where appropriate.

Indexed as

AnimalsATP-Binding Cassette TransportersDatabases, PharmaceuticalHumansIon ChannelsLigandsPharmaceutical PreparationsReceptors, Cell SurfaceReceptors, Cytoplasmic and NuclearATP-Binding Cassette TransportersIon ChannelsLigandsPharmaceutical PreparationsReceptors, Cell SurfaceReceptors, Cytoplasmic and Nuclear

Identifiers

PMID31710713
PMCPMC6844579

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.