Evidence map›Paper›PMID 31710517›Full record

ArticleAmerican journal of respiratory and critical care medicine2020

Genome-Wide Association Study of Susceptibility to Idiopathic Pulmonary Fibrosis.

Richard J Allen, Beatriz Guillen-Guio, Justin M Oldham, Shwu-Fan Ma, Amy Dressen, Megan L Paynton, Luke M Kraven, Ma'en Obeidat, Xuan Li, Michael Ng and 56 more

Open access · hybridAbstract read
In one paragraph

Article in American journal of respiratory and critical care medicine, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 205 papers, 7 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
205citing papers in PubMed, 7 pooled it
30.3field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

205 citing papers in PubMed, 7 syntheses or guidelines pooled it, 330 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Common single nucleotide polymorphisms associated with idiopathic pulmonary fibrosis: a systematic review.European respiratory review : an official journal of the European Respiratory Society · 2024
    Pooled it
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  8. Trial
  9. Article
  10. Article
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  12. Multi-omics insights into the mechanisms and prognosis of IPF.Genes and environment : the official journal of the Japanese Environmental Mutagen Society · 2026
    Review
  13. Early-life internalizing behavioral trajectories and childhood-onset asthma: An epigenetic link.Pediatric allergy and immunology : official publication of the European Society of Pediatric Allergy and Immunology · 2026
    Article
  14. Article
  15. Article
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  20. Article

145 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

66 authors at 20 institutions in 7 countries.

Richard J AllenDepartment of Health Sciences, University of Leicester, Leicester, United Kingdom.ORCID 0000-0002-8450-3056
Beatriz Guillen-GuioUnidad de Investigacion, Hospital Universitario Ntra. Sra. de Candelaria and.
Justin M OldhamDepartment of Internal Medicine, University of California Davis, Davis, California.
Shwu-Fan MaDivision of Pulmonary and Critical Care Medicine.
Amy DressenGenentech, South San Francisco, California.
Megan L PayntonDepartment of Health Sciences, University of Leicester, Leicester, United Kingdom.ORCID 0000-0002-3657-8205
Luke M KravenDepartment of Health Sciences, University of Leicester, Leicester, United Kingdom.
Ma'en ObeidatThe University of British Columbia Centre for Heart Lung Innovation, St. Paul's Hospital, Vancouver, British Columbia, Canada.
Xuan LiThe University of British Columbia Centre for Heart Lung Innovation, St. Paul's Hospital, Vancouver, British Columbia, Canada.
Michael NgNuffield Department of Orthopaedics, Rheumatology and Musculoskeletal Sciences.
Rebecca BraybrookeDivision of Epidemiology and Public Health and.
Maria Molina-MolinaServei de Pneumologia, Laboratori de Pneumologia Experimental, Instituto de Investigación Biomédica de Bellvitge (IDIBELL), Barcelona, Spain.
Brian D HobbsChanning Division of Network Medicine.ORCID 0000-0001-9564-0745
Rachel K PutmanDivision of Pulmonary and Critical Care Medicine.
Phuwanat SakornsakolpatChanning Division of Network Medicine.ORCID 0000-0002-4308-0974
Helen L BoothDepartment of Thoracic Medicine, University College London Hospitals NHS Foundation Trust, London, United Kingdom.
William A FahyDiscovery Medicine, GlaxoSmithKline, Stevenage, United Kingdom.
Simon P HartRespiratory Research Group, Hull York Medical School, Castle Hill Hospital, Cottingham, United Kingdom.
Mike R HillClinical Trial Service Unit and Epidemiological Studies Unit, Nuffield Department of Population Health.
Nik HiraniMedical Research Council Centre for Inflammation Research, The University of Edinburgh, Edinburgh, United Kingdom.
Richard B HubbardDivision of Epidemiology and Public Health and.
Robin J McAnultyUCL Respiratory Centre for Inflammation and Tissue Repair, University College London, London, United Kingdom.
Ann B MillarAcademic Respiratory Unit, School of Clinical Sciences, University of Bristol, Bristol, United Kingdom.
Vidyia NavaratnamDivision of Epidemiology and Public Health and.ORCID 0000-0002-2914-8012
Eunice OballaDiscovery Medicine, GlaxoSmithKline, Stevenage, United Kingdom.
Helen ParfreyCambridge Interstitial Lung Disease Service, Royal Papworth Hospital, Cambridge, United Kingdom.
Gauri SainiRespiratory Medicine, Nottingham University Hospitals NHS Trust, Nottingham, United Kingdom.ORCID 0000-0002-7786-737X
Moira K B WhyteMedical Research Council Centre for Inflammation Research, The University of Edinburgh, Edinburgh, United Kingdom.
Yingze ZhangDivision of Pulmonary, Allergy and Critical Care Medicine and.
Naftali KaminskiSection of Pulmonary, Critical Care and Sleep Medicine, Yale School of Medicine, New Haven, Connecticut.
Ayodeji AdegunsoyeSection of Pulmonary and Critical Care, Department of Medicine, The University of Chicago, Chicago, Illinois.
Mary E StrekSection of Pulmonary and Critical Care, Department of Medicine, The University of Chicago, Chicago, Illinois.
Margaret NeighborsGenentech, South San Francisco, California.
Xuting R ShengGenentech, South San Francisco, California.
Gunnar GudmundssonDepartment of Respiratory Medicine, Landspital University Hospital, Reykjavik, Iceland.
Vilmundur GudnasonFaculty of Medicine University of Iceland, Reykjavik, Iceland.
Hiroto HatabuDepartment of Radiology, and.
David J LedererDepartment of Medicine, College of Physicians and Surgeons and.ORCID 0000-0001-5258-0228
Ani ManichaikulCenter for Public Health Genomics, and.
John D NewellDivision of Cardiovascular and Pulmonary Imaging, Department of Radiology, University of Iowa Carver College of Medicine, Iowa City, Iowa.
George T O'ConnorDepartment of Medicine, Pulmonary Center, Boston University, Boston, Massachusetts.
Victor E OrtegaCenter for Precision Medicine, Department of Internal Medicine, Wake Forest School of Medicine, Winston-Salem, North Carolina.
Hanfei XuDepartment of Biostatistics, Boston University School of Public Health, Boston, Massachusetts.
Tasha E FingerlinCenter for Genes, Environment and Health, National Jewish Health, Denver, Colarado.
Yohan BosséInstitut universitaire de cardiologie et de pneumologie de Québec, Université Laval, Québec, Québec, Canada.ORCID 0000-0002-3067-3711
Ke HaoDepartment of Genetics and Genomic Sciences and.
Philippe JoubertInstitut universitaire de cardiologie et de pneumologie de Québec, Université Laval, Québec, Québec, Canada.
David C NickleMerck Research Laboratories, Genetics and Pharmacogenomics, Boston, Massachusetts.
Don D SinThe University of British Columbia Centre for Heart Lung Innovation, St. Paul's Hospital, Vancouver, British Columbia, Canada.
Wim TimensUniversity Medical Center Groningen, University of Groningen, Department of Pathology and Medical Biology and.ORCID 0000-0002-4146-6363
Dominic FurnissNuffield Department of Orthopaedics, Rheumatology and Musculoskeletal Sciences.
Andrew P MorrisWellcome Centre for Human Genetics, and.
Krina T ZondervanWellcome Centre for Human Genetics, and.
Ian P HallDivision of Respiratory Medicine, University of Nottingham, Nottingham, United Kingdom.ORCID 0000-0001-9933-3216
Ian SayersDivision of Respiratory Medicine, University of Nottingham, Nottingham, United Kingdom.
Martin D TobinDepartment of Health Sciences, University of Leicester, Leicester, United Kingdom.
Toby M MaherNational Institute for Health Research Respiratory Clinical Research Facility, Royal Brompton Hospital, London, United Kingdom.
Michael H ChoChanning Division of Network Medicine.
Gary M HunninghakeDivision of Pulmonary and Critical Care Medicine.
David A SchwartzCenter for Genes, Environment and Health, National Jewish Health, Denver, Colarado.
Brian L YaspanGenentech, South San Francisco, California.
Philip L MolyneauxNational Institute for Health Research Respiratory Clinical Research Facility, Royal Brompton Hospital, London, United Kingdom.
Carlos FloresUnidad de Investigacion, Hospital Universitario Ntra. Sra. de Candelaria and.ORCID 0000-0001-5352-069X
Imre NothDivision of Pulmonary and Critical Care Medicine.
R Gisli JenkinsDivision of Respiratory Medicine, University of Nottingham, Nottingham, United Kingdom.
Louise V WainDepartment of Health Sciences, University of Leicester, Leicester, United Kingdom.ORCID 0000-0003-4951-1867
National Institute for Health Research · GBPulmonary and Critical Care Associates · USUniversity of Leicester · GBCentre for Inflammation Research · GBUniversity of British Columbia · CAUniversity of Nottingham · GBBoston University · USBrigham and Women's Hospital · USCentre for Human Genetics · GBGlaxoSmithKline (United Kingdom) · GBInstitut universitaire de cardiologie et de pneumologie de Québec · CANational Jewish Health · USNuffield Orthopaedic Centre · GBUniversidad de La Laguna · ESUniversity of Chicago · USUniversity of Iceland · ISCastle Hill Hospital · GBIcahn School of Medicine at Mount Sinai · USInstituto de Salud Carlos III · ESMerck & Co., Inc., Rahway, NJ, USA (United States) · US

Funding

UCLA Clinical Translational Science InstituteUL1TR001881 · NCATS · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI ARLEEN F. BROWN, ARASH NAEIM · 2016 to 2026
$118.1M
Yale Clinical and Translational Science Award (U Component)UL1TR001863 · NCATS · YALE UNIVERSITY · PI John H. Krystal, LUCILA OHNO-MACHADO · 2016 to 2026
$102.9M
Institute for Clinical and Translational ResearchUL1TR001079 · NCATS · JOHNS HOPKINS UNIVERSITY · PI FORD, DANIEL ERNEST · 2013 to 2017
$60.1M
Transgenic & Knock-out MouseP30DK063491 · NIDDK · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI Andrea L Hevener · 2003 to 2026
$40.4M
Wake Forest Clinical and Translational Science AwardUL1TR001420 · NCATS · WAKE FOREST UNIVERSITY HEALTH SCIENCES · PI ARD, JAMY D, FOLEY, KRISTIE L · 2015 to 2023
$32.3M
Clinical and Translational Science AwardUL1TR000040 · NCATS · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI GINSBERG, HENRY N · 2012 to 2015
$26.2M
Mechanisms of Familial Pulmonary FibrosisP01HL092870 · NHLBI · VANDERBILT UNIVERSITY MEDICAL CENTER · PI SCHWARTZ, DAVID ALBERT · 2010 to 2020
$21.6M
MULTIDISCIPLINARY RESPIRATORY DISEASES RESEARCH TRAININGT32HL007085 · NHLBI · UNIVERSITY OF COLORADO DENVER · PI ELLEN L BURNHAM, LISA A MAIER · 1985 to 2026
$21.6M
Role of Genetics in Idiopathic Pulmonary Fibrosis (IPF)R01HL097163 · NHLBI · UNIVERSITY OF COLORADO DENVER · PI FINGERLIN, TASHA E., SCHWARTZ, DAVID ALBERT · 2009 to 2018
$16.4M
Clinical Genetics and Screening for Pulmonary FibrosisR01HL130974 · NHLBI · BRIGHAM AND WOMEN'S HOSPITAL · PI GARY MATTHEW HUNNINGHAKE, Benjamin Alexander Raby · 2016 to 2026
$10.0M
Genetic and Genomic Characterization of the Occurrence and Progression of Interstitial Lung AbnormalitiesR01HL135142 · NHLBI · BRIGHAM AND WOMEN'S HOSPITAL · PI MICHAEL H. CHO, GARY MATTHEW HUNNINGHAKE · 2017 to 2026
$7.7M
Subclinical Interstitial Lung Disease in MESA and FAR-ILDR01HL103676 · NHLBI · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI GARCIA, CHRISTINE KIM · 2011 to 2020
$6.4M
Department of Health CS-2013-13-017Department of Health RP-2017-08-ST2-014HSRD VA CDA 13-017Medical Research Council G0901226Medical Research Council G1000861Medical Research Council MC_PC_12010Medical Research Council MC_U137686855Medical Research Council MR/N005953/1NCATS NIH HHS UL1 TR000040NCATS NIH HHS UL1 TR001079NCATS NIH HHS UL1 TR001420NCATS NIH HHS UL1 TR001863NCATS NIH HHS UL1 TR001881NHLBI NIH HHS HHSN268201500003CNHLBI NIH HHS HHSN268201500003INHLBI NIH HHS K08 HL136928NHLBI NIH HHS K08 HL140087NHLBI NIH HHS K23 HL138190NHLBI NIH HHS N01 HC095159NHLBI NIH HHS N01 HC095160NHLBI NIH HHS N01 HC095161NHLBI NIH HHS N01 HC095162NHLBI NIH HHS N01 HC095163NHLBI NIH HHS N01 HC095164NHLBI NIH HHS N01 HC095165NHLBI NIH HHS N01 HC095166NHLBI NIH HHS N01 HC095167NHLBI NIH HHS N01 HC095168NHLBI NIH HHS N01 HC095169NHLBI NIH HHS N02 HL064278NHLBI NIH HHS P01 HL092870NHLBI NIH HHS R01 HL097163NHLBI NIH HHS R01 HL103676NHLBI NIH HHS R01 HL111024NHLBI NIH HHS R01 HL113264NHLBI NIH HHS R01 HL130796NHLBI NIH HHS R01 HL130974NHLBI NIH HHS R01 HL131565NHLBI NIH HHS R01 HL135142NHLBI NIH HHS R01 HL137234NHLBI NIH HHS R01 HL137927NHLBI NIH HHS R01 HL149836NHLBI NIH HHS R33 HL120770NHLBI NIH HHS T32 HL007085NHLBI NIH HHS UG3 HL151865NHLBI NIH HHS UH3 HL151865NIDDK NIH HHS P30 DK063491NIH HHS HHSN263201500003IWellcome TrustWellcome Trust 097152/Z/11/ZWellcome Trust WT202849/Z/16/Z
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

AgedCase-Control StudiesCell Cycle ProteinsFemaleGene ExpressionGenetic Predisposition to DiseaseGenome-Wide Association StudyHumansIdiopathic Pulmonary FibrosisIntracellular Signaling Peptides and ProteinsKinesinsMaleMiddle AgedRisk AssessmentSignal TransductionSpindle ApparatusCell Cycle ProteinsDEPTOR protein, humanIntracellular Signaling Peptides and ProteinsKIF15 protein, humanKinesinsMAD1L1 protein, humanTOR Serine-Threonine KinasesDEPTORepidemiologygeneticsKIF15MAD1L1

Identifiers

PMID31710517
PMCPMC7047454
OpenAlexW2983449145

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.