Evidence map›Paper›PMID 31710292›Full record

ArticleeLife2019

Initiation of chromosome replication controls both division and replication cycles in

Guillaume Witz, Erik van Nimwegen, Thomas Julou

Open access · goldAbstract read
In one paragraph

Article in eLife, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 34 papers.

0numbers the graph read from it
0cells of the map it votes in
34citing papers in PubMed
2.7field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

34 citing papers in PubMed, 80 citations in OpenAlex.

  1. Review
  2. Review
  3. Article
  4. Article
  5. Article
  6. Article
  7. Characterizing Common Factors Affecting Replication Initiation During HInternational journal of molecular sciences · 2025
    Article
  8. Article
  9. Article
  10. Review
  11. Article
  12. Article
  13. Article
  14. Creating Polyploid Escherichia Coli and Its Application in Efficient L-Threonine Production.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2023
    Article
  15. Article
  16. Regulatory elements coordinating initiation of chromosome replication to theProceedings of the National Academy of Sciences of the United States of America · 2023
    Article
  17. Article
  18. Recollections of a Helmstetter Disciple.Life (Basel, Switzerland) · 2023
    Review
  19. Using conditional independence tests to elucidate causal links in cell cycle regulation inProceedings of the National Academy of Sciences of the United States of America · 2023
    Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Guillaume WitzBiozentrum, University of Basel, Basel, Switzerland.ORCID 0000-0003-1562-4265
Erik van NimwegenBiozentrum, University of Basel, Basel, Switzerland.
Thomas JulouBiozentrum, University of Basel, Basel, Switzerland.ORCID 0000-0001-7123-198X
University of Bern · CH

Funding

Schweizerischer Nationalfonds zur Förderung der Wissenschaftlichen Forschung 31003A_159673Schweizerischer Nationalfonds zur Förderung der Wissenschaftlichen Forschung PZ00P3_161467
6 · The paper itself

Abstract

Living cells proliferate by completing and coordinating two cycles, a division cycle controlling cell size and a DNA replication cycle controlling the number of chromosomal copies. It remains unclear how bacteria such as

Indexed as

Cell CycleCell DivisionChromosomes, BacterialDNA, BacterialDNA ReplicationEscherichia coliMicrofluidic Analytical TechniquesMicroscopy, FluorescenceMicroscopy, Phase-ContrastModels, GeneticSingle-Cell AnalysisTime-Lapse ImagingDNA, Bacterialadderbacterial cell divisioncell cyclecomputational biologyE. colifluorescence microscopyinfectious diseasemicrobiologymicrofluidicsreplication initiationsystems biology

Identifiers

PMID31710292
PMCPMC6890467
OpenAlexW2986320500

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.