Evidence map›Paper›PMID 31710291›Full record

ArticleeLife2019

The DNA-binding protein HTa from

Antoine Hocher, Maria Rojec, Jacob B Swadling, Alexander Esin, Tobias Warnecke

Open access · goldAbstract read
In one paragraph

Article in eLife, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed
2.5field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 29 citations in OpenAlex.

  1. Chromatin and gene regulation in archaea.Molecular microbiology · 2025
    Review
  2. Review
  3. Review
  4. Article
  5. Article
  6. Article
  7. Article
  8. ImprovingHeliyon · 2023
    Article
  9. Article
  10. Review
  11. Article
  12. Progress and Challenges in Studying the Ecophysiology of Archaea.Methods in molecular biology (Clifton, N.J.) · 2022
    Article
  13. Article
  14. Review
  15. Article
  16. Article
  17. Article
  18. Chromatinization ofeLife · 2019
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Antoine HocherMRC London Institute of Medical Sciences (LMS), London, United Kingdom.
Maria RojecMRC London Institute of Medical Sciences (LMS), London, United Kingdom.
Jacob B SwadlingMRC London Institute of Medical Sciences (LMS), London, United Kingdom.
Alexander EsinMRC London Institute of Medical Sciences (LMS), London, United Kingdom.
Tobias WarneckeMRC London Institute of Medical Sciences (LMS), London, United Kingdom.ORCID 0000-0002-4936-5428
NIHR Imperial Biomedical Research Centre · GB

Funding

Medical Research Council MC_A658_5TY40Medical Research Council MC_UP_1102/7
6 · The paper itself

Abstract

Histones are a principal constituent of chromatin in eukaryotes and fundamental to our understanding of eukaryotic gene regulation. In archaea, histones are widespread but not universal: several lineages have lost histone genes. What prompted or facilitated these losses and how archaea without histones organize their chromatin remains largely unknown. Here, we elucidate primary chromatin architecture in an archaeon without histones,

Indexed as

Sequence Homology, Amino AcidAmino Acid SequenceArchaeal ProteinsBase CompositionChromatinDNA-Binding ProteinsEscherichia coliHistonesModels, MolecularPhylogenyProtein BindingProtein MultimerizationThermoplasmaTranscription Initiation SiteArchaeal ProteinsChromatinDNA-Binding ProteinsHistonesarchaeachromatinchromosomesconvergent evolutionevolutionary biologygene expressionhistonesMethanothermus fervidusThermoplasma acidophilum

Identifiers

PMID31710291
PMCPMC6877293
OpenAlexW2987525383

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.