Evidence map›Paper›PMID 31709676›Full record

ReviewChembiochem : a European journal of chemical biology2020

New Vocabulary for Bacterial Communication.

Nicholas J Tobias, Jannis Brehm, Darko Kresovic, Sophie Brameyer, Helge B Bode, Ralf Heermann

Open access · hybridAbstract readReview
In one paragraph

Review in Chembiochem : a European journal of chemical biology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.

0numbers the graph read from it
0cells of the map it votes in
24citing papers in PubMed
4.4field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

24 citing papers in PubMed, 59 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Chemical Conversations.Molecules (Basel, Switzerland) · 2025
    Review
  5. Article
  6. Review
  7. Article
  8. Article
  9. Review
  10. Article
  11. Article
  12. The quorum quenching enzyme Aii20J modifiesFrontiers in cellular and infection microbiology · 2023
    Article
  13. Review
  14. Article
  15. "Universal" Antimicrobial Combination of Bacitracin and HisInternational journal of molecular sciences · 2022
    Article
  16. Article
  17. Review
  18. Article
  19. Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 1 country.

Nicholas J TobiasFachbereich Biowissenschaften, Merck-Stiftungsprofessur für Molekulare Biotechnologie, Goethe-Universität Frankfurt, Max-von-Laue-Strasse 9, 60438, Frankfurt am Main, Germany.ORCID 0000-0003-2725-3043
Jannis BrehmInstitut für Molekulare Physiologie, Mikrobiologie und Weinforschung, Johannes-Gutenberg-Universität Mainz, Johann-Joachim-Becher-Weg 13, 55128, Mainz, Germany.
Darko KresovicFachbereich Biowissenschaften, Merck-Stiftungsprofessur für Molekulare Biotechnologie, Goethe-Universität Frankfurt, Max-von-Laue-Strasse 9, 60438, Frankfurt am Main, Germany.
Sophie BrameyerBiozentrum, Bereich Mikrobiologie, Ludwig-Maximilians-Universität München, Großhaderner Strasse 2-4, 82152, Martinsried, Germany.
Helge B BodeFachbereich Biowissenschaften, Merck-Stiftungsprofessur für Molekulare Biotechnologie, Goethe-Universität Frankfurt, Max-von-Laue-Strasse 9, 60438, Frankfurt am Main, Germany.ORCID 0000-0001-6048-5909
Ralf HeermannInstitut für Molekulare Physiologie, Mikrobiologie und Weinforschung, Johannes-Gutenberg-Universität Mainz, Johann-Joachim-Becher-Weg 13, 55128, Mainz, Germany.ORCID 0000-0003-0631-6156
Goethe University Frankfurt · DEJohannes Gutenberg University Mainz · DELudwig-Maximilians-Universität München · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Quorum sensing (QS) is widely accepted as a procedure that bacteria use to converse. However, prevailing thinking places acyl homoserine lactones (AHLs) at the forefront of this communication pathway in Gram-negative bacteria. With the advent of high-throughput genomics and the subsequent influx of bacterial genomes, bioinformatics analysis has determined that the genes encoding AHL biosynthesis, originally discovered to be indispensable for QS (LuxI-like proteins and homologues), are often absent in QS-capable bacteria. Instead, the sensing protein (LuxR-like proteins) is present with an apparent inability to produce any outgoing AHL signal. Recently, several signals for these LuxR solos have been identified. Herein, advances in the field of QS are discussed, with a particular focus on recent research in the field of bacterial cell-cell communication.

Indexed as

Acyl-ButyrolactonesCell CommunicationGram-Negative BacteriaQuorum SensingAcyl-Butyrolactonesbacterial communicationbiosynthesisgene sequencingquorum quenchingquorum sensing

Identifiers

PMID31709676
PMCPMC7154725
OpenAlexW2989396684

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.