ArticleInternational journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics2020
Postpartum hemorrhage care bundles to improve adherence to guidelines: A WHO technical consultation.
Article in International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07005349 (Rule of THUMB), which is not on this map. Cited by 56 papers, 7 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Rule of THUMB: A Multi-centre Cluster Trial Evaluating the Implementation of a Perioperative Care Complex Intervention to Improve Outcomes From Haemorrhage During and After Caesarean Section in African Hospitals
Who cites it
56 citing papers in PubMed, 7 syntheses or guidelines pooled it, 112 citations in OpenAlex.
- Association between postpartum depression and postpartum hemorrhage: A systematic review and meta-analysis.Acta obstetricia et gynecologica Scandinavica · 2024Pooled it
- Pooled it
- Perceptions and experiences of the prevention, detection, and management of postpartum haemorrhage: a qualitative evidence synthesis.The Cochrane database of systematic reviews · 2023Pooled it
- Comparison of Clinical Efficacy and Safety between Misoprostol and Oxytocin in the Prevention of Postpartum Hemorrhage: A Meta-Analysis.Journal of healthcare engineering · 2022Pooled it
- The cost-effectiveness of tranexamic acid for treatment of postpartum hemorrhage: A systematic review.International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics · 2021Pooled it
- Pooled it
- Cost-effectiveness of uterine tamponade devices for the treatment of postpartum hemorrhage: A systematic review.International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics · 2020Pooled it
- Suction tube uterine tamponade versus uterine balloon tamponade for treatment of refractory postpartum hemorrhage: A randomized clinical feasibility trial.International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics · 2025Trial
- Early detection and a treatment bundle strategy for postpartum haemorrhage: a mixed-methods process evaluation.The Lancet. Global health · 2025Trial
- A cost-effectiveness analysis of early detection and bundled treatment of postpartum hemorrhage alongside the E-MOTIVE trial.Nature medicine · 2024Trial
- OASI2: a cluster randomised hybrid evaluation of strategies for sustainable implementation of the Obstetric Anal Sphincter Injury Care Bundle in maternity units in Great Britain.Implementation science : IS · 2021Trial
- Postpartum hemorrhage in Suriname: A national descriptive study of hospital births and an audit of case management.PloS one · 2020Trial
- Availability, cost, and budget impact of lifesaving postpartum hemorrhage interventions in public hospitals in Zambia: A cross-sectional survey.International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics · 2026Article
- Innovative Approach for Rapid Control of Postpartum Hemorrhage With Abdominal Pressure.Maternal-fetal medicine (Wolters Kluwer Health, Inc.) · 2026Article
- Management of obstetric and gynecologic hemorrhage: a narrative review of current guidelines and evidence.Journal of medicine and life · 2026Review
- Global, Regional, and National Epidemiology of Postpartum Hemorrhage (1990-2021): A Statistical Analysis of Incidence, Mortality, and DALYs.Health science reports · 2026Article
- From Pledge to Practice: A Call for FIGO/WHO to Issue Harmonized, Consolidated Abortion Care Guidelines.Public health challenges · 2026Article
- Feasibility, acceptability, and effectiveness of the E-MOTIVE bundle intervention for early detection and management of postpartum hemorrhage in a low-middle-income country: implementation research.AJOG global reports · 2026Article
- Scaling up implementation of the E-MOTIVE bundle for early detection and management of postpartum haemorrhage emergencies: A scoping review.Health SA = SA Gesondheid · 2026Review
- Introducing the E-MOTIVE Bundle for the Management of Postpartum Hemorrhage: Perceptions of Health Professionals and Perceived Barriers to Its Implementation in Sub-Saharan Africa.Journal of pregnancy · 2026Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
27 authors at 20 institutions in 13 countries.
Funding
Abstract
objectiveTo systematically develop evidence-based bundles for care of postpartum hemorrhage (PPH).
methodsAn international technical consultation was conducted in 2017 to develop draft bundles of clinical interventions for PPH taken from the WHO's 2012 and 2017 PPH recommendations and based on the validated "GRADE Evidence-to-Decision" framework. Twenty-three global maternal-health experts participated in the development process, which was informed by a systematic literature search on bundle definitions, designs, and implementation experiences. Over a 6-month period, the expert panel met online and via teleconferences, culminating in a 2-day in-person meeting.
resultsThe consultation led to the definition of two care bundles for facility implementation. The "first response to PPH bundle" comprises uterotonics, isotonic crystalloids, tranexamic acid, and uterine massage. The "response to refractory PPH bundle" comprises compressive measures (aortic or bimanual uterine compression), the non-pneumatic antishock garment, and intrauterine balloon tamponade (IBT). Advocacy, training, teamwork, communication, and use of best clinical practices were defined as PPH bundle supporting elements.
conclusionFor the first response bundle, further research should assess its feasibility, acceptability, and effectiveness; and identify optimal implementation strategies. For the response to refractory bundle, further research should address pending controversies, including the operational definition of refractory PPH and effectiveness of IBT devices.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.