Evidence map›Paper›PMID 31709307›Full record

ArticleClinical and translational radiation oncology2020

Acceptable fetal dose using flattening filter-free volumetric arc therapy (FFF VMAT) in postoperative chemoradiotherapy of tongue cancer during pregnancy.

Wataru Takahashi, Kanabu Nawa, Akihiro Haga, Hideomi Yamashita, Toshikazu Imae, Mami Ogita, Kae Okuma, Osamu Abe, Keiichi Nakagawa

Open access · goldAbstract readCase Reports
PubMed Full text at PMC Publisher
In one paragraph

Article in Clinical and translational radiation oncology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.4field-weighted citation impact, top 33% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 8 citations in OpenAlex.

  1. Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 1 country.

Wataru TakahashiDepartment of Radiology, The University of Tokyo Hospital, Tokyo, Japan.
Kanabu NawaDepartment of Radiology, The University of Tokyo Hospital, Tokyo, Japan.
Akihiro HagaDepartment of Medical Image Informatics, Tokushima University, Tokushima, Japan.
Hideomi YamashitaDepartment of Radiology, The University of Tokyo Hospital, Tokyo, Japan.
Toshikazu ImaeDepartment of Radiology, The University of Tokyo Hospital, Tokyo, Japan.
Mami OgitaDepartment of Radiology, The University of Tokyo Hospital, Tokyo, Japan.
Kae OkumaDepartment of Radiology, The University of Tokyo Hospital, Tokyo, Japan.
Osamu AbeDepartment of Radiology, The University of Tokyo Hospital, Tokyo, Japan.
Keiichi NakagawaDepartment of Radiology, The University of Tokyo Hospital, Tokyo, Japan.
University of Tokyo Hospital · JPTokushima University · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Optimizing irradiation protocols for pregnant women is challenging, because there are few cases and a dearth of fetal dosimetry data. We cared for a 36-year-old pregnant woman with tongue cancer. Prior to treatment, we compared three intensity-modulated radiation therapy (IMRT) techniques, including helical tomotherapy, volumetric arc therapy (VMAT), and flattening-filter free VMAT (FFF-VMAT) using treatment planning software. FFF-VMAT achieved the minimum fetal exposure and was selected as the optimal modality. We prescribed 66 Gy to the involved nodes, 60 Gy to the tumor bed and ipsilateral neck, and 54 Gy to the contralateral neck over 33 fractions. To confirm the out-of-field exposure per fraction, surface doses and the rectal dose were measured during FFF-VMAT delivery. Postoperative chemoradiotherapy was delivered using IMRT and a cisplatin regimen. Without any shielding, the total fetal dose was 0.03 Gy, within the limits established by the ICRP. A healthy girl was born vaginally at 37 weeks' gestation.

Indexed as

Fetal doseFlattening filter-freeIntensity-modulated radiation therapyPregnancyTongue cancer

Identifiers

PMID31709307
PMCPMC6833340
OpenAlexW2981083159

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.