Evidence map›Paper›PMID 31709296›Full record

ArticleOne health (Amsterdam, Netherlands)2019

Low seroprevalence of hepatitis E on Reunion island.

Patrick Gérardin, Vincent Porphyre, Anita Tsatoromila, Laurent Cuissard, Jean-Philippe Becquart, Karim Boussaid, Antoine Bertolotti, Florence Naze, Sandrine Picot, Laurent Filleul and 4 more

Abstract read
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In one paragraph

Article in One health (Amsterdam, Netherlands), 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Patrick GérardinINSERM Centre d'Investigation Clinique 1410 Epidémiologie Clinique, Centre Hospitalier Universitaire (CHU), Réunion, Saint Pierre, Reunion.
Vincent PorphyreUMR SELMET, Centre de coopération internationale en recherche agronomique pour le développement (CIRAD), Saint Pierre, Reunion, UMR SELMET, Université de Montpellier, CIRAD, INRA, Montpellier SupAgro, Montpellier, France.
Anita TsatoromilaLaboratoire de Microbiologie, CHU Réunion, Saint Denis, Saint Pierre, Reunion.
Laurent CuissardService d'Hépato-Gastroentérologie, Centre Hospitalier de l'Ouest Réunion, Saint Paul, Reunion.
Jean-Philippe BecquartService d'Hépato-Gastroentérologie, CHU Réunion, Saint Pierre, Reunion.
Karim BoussaidINSERM Centre d'Investigation Clinique 1410 Epidémiologie Clinique, Centre Hospitalier Universitaire (CHU), Réunion, Saint Pierre, Reunion.
Antoine BertolottiINSERM Centre d'Investigation Clinique 1410 Epidémiologie Clinique, Centre Hospitalier Universitaire (CHU), Réunion, Saint Pierre, Reunion.
Florence NazeLaboratoire de Microbiologie, CHU Réunion, Saint Denis, Saint Pierre, Reunion.
Sandrine PicotLaboratoire de Microbiologie, CHU Réunion, Saint Denis, Saint Pierre, Reunion.
Laurent FilleulCellule d'Intervention Régionale et d'Epidémiologie Océan Indien, Santé Publique France, French National Public Health Agency, Saint Denis, Reunion.
Pablo TortosaUM 134 PIMIT Processus Infectieux en Milieu Insulaire Tropical. Université de La Réunion, INSERM 1187, CNRS 9192, IRD 249, CYROI, Sainte Clotilde, Reunion.
Julien JaubertLaboratoire de Microbiologie, CHU Réunion, Saint Denis, Saint Pierre, Reunion.
Vanina GuernierGeelong Centre for Emerging Infectious Diseases, Deakin University, Geelong, Victoria, Australia.
Hervé PascalisUM 134 PIMIT Processus Infectieux en Milieu Insulaire Tropical. Université de La Réunion, INSERM 1187, CNRS 9192, IRD 249, CYROI, Sainte Clotilde, Reunion.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveHepatitis E virus (HEV) has been scarcely investigated in the Indian Ocean. Following a nationwide serosurvey among blood donors, we conducted a population-based serosurvey to assess the magnitude of HEV exposure on Reunion Island.

methodsFour hundred and sixty-six archived frozen human sera from the 2009 CoPanFlu-RUN cohort were analysed using the Wantai HEV IgG enzyme immunoassay. HEV seropositivity was defined as an IgG titre ≥5 UI/ml. Raw and weighted seroprevalences were assessed to account for the discrepancy between the CoPanFlu-RUN subset and the general community. Prevalence proportion ratios (PPR) were measured using log-binomial models.

resultsThe raw and the weighted seroprevalences of HEV were 9.01% (95% CI 6.41-11.61) and 6.73% (95% CI 4.47-8.98), respectively. The presence of HEV IgG antibodies was associated with increasing age (

conclusionReunion Island is a low endemic area for HEV exposure. Despite limitations related to the retrospective study design, our findings confirm the roles of cumulative lifetime exposure and male gender in HEV exposure. The risk associated with neighbouring pig farms might also suggest environmental contamination in this setting.

Indexed as

General populationHepatitis EImmunoassayPig farmPrevalenceSeroepidemiological studySerologySerosurveyStored frozen serumZoonosis

Identifiers

PMID31709296
PMCPMC6831862

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.