Evidence map›Paper›PMID 31709234›Full record

ArticleFrontiers in chemistry2019

A Surface-Enhanced Raman Spectral Library of Important Drugs Associated With Point-of-Care and Field Applications.

Stuart Farquharson, Carl Brouillette, Wayne Smith, Chetan Shende

Open access · goldAbstract read
In one paragraph

Article in Frontiers in chemistry, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
5.3field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 53 citations in OpenAlex.

  1. Article
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  7. Interpol Review of Drug Analysis 2019-2022.Forensic science international. Synergy · 2023
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Stuart FarquharsonReal-Time Analyzers, Inc., Middletown, CT, United States.
Carl BrouilletteReal-Time Analyzers, Inc., Middletown, CT, United States.
Wayne SmithReal-Time Analyzers, Inc., Middletown, CT, United States.
Chetan ShendeReal-Time Analyzers, Inc., Middletown, CT, United States.
Real Time Analyzers (United States) · US

Funding

Saliva Analyzer for Diagnosing SRD Patient Drug UseR44DA032178 · NIDA · REAL-TIME ANALYZERS, INC. · PI FARQUHARSON, STUART · 2014 to 2015
$1.0M
CLC NIH HHS C0000008NIDA NIH HHS R44 DA032178
6 · The paper itself

Abstract

During the past decade, the ability of surface-enhanced Raman spectroscopy (SERS) to measure extremely low concentrations, such as mg/L and below, and the availability of hand-held Raman spectrometers, has led to a significant growth in the number and variety of applications of SERS to real-world problems. Most of these applications involve the measurement of drugs, such as quantifying medication in patients, identifying illicit drugs in impaired drivers, and more recently, identifying drugs used as weapons. Similar to Raman spectroscopy, most of the point-of-care and field applications involve the identification of the drug to determine the course of action. However, unlike Raman spectroscopy, spectral libraries are not readily available to perform the necessary identification. In a large part, this is due to the uniqueness of the commercially available SERS substrates, each of which can produce different spectra for the same drug. In an effort to overcome this limitation, we have measured numerous drugs using the most common, and readily available SERS material and hand-held Raman analyzers, specifically gold colloids and analyzers using 785 nm laser excitation. Here we present the spectra of some 39 drugs of current interest, such as buprenorphine, delta-9 tetrahydrocannabinol, and fentanyl, which we hope will aid in the development of current and future SERS drug analysis applications.

Indexed as

buprenorphinecannabisdrug analysisfentanylopioidsSERSspectral librarytrace analysis

Identifiers

PMID31709234
PMCPMC6823623
OpenAlexW2981839333

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.