Evidence map›Paper›PMID 31708898›Full record

ArticleFrontiers in microbiology2019

Inhibition by Marine Algae of Chikungunya Virus Isolated From Patients in a Recent Disease Outbreak in Rio de Janeiro.

Claudio Cesar Cirne-Santos, Caroline de Souza Barros, Caio Cesar Richter Nogueira, Renata Campos Azevedo, Kristie Aimi Yamamoto, Guilherme Louzada Silva Meira, Zilton Farias Meira de Vasconcelos, Norman Arthur Ratcliffe, Valéria Laneuville Teixeira, Jonas Schmidt-Chanasit and 2 more

Open access · goldAbstract read
In one paragraph

Article in Frontiers in microbiology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
4.3field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 33 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Antiviral Activity ofCurrent topics in medicinal chemistry · 2024
    Article
  6. Review
  7. Article
  8. Green algaeNarra J · 2023
    Article
  9. Exploring the therapeutic potential of marine-derived bioactive compounds against COVID-19.Environmental science and pollution research international · 2021
    Review
  10. Review
  11. Broad Spectrum Algae Compounds Against Viruses.Frontiers in microbiology · 2021
    Review
  12. Article
  13. Review
  14. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 7 institutions in 4 countries.

Claudio Cesar Cirne-SantosLaboratório de Virologia Molecular e Biotecnologia Marinha, Programa de Pós-graduação em Ciências e Biotecnologia, Departamento de Biologia Celular e Molecular, Instituto de Biologia, Universidade Federal Fluminense, Niterói, Brazil.
Caroline de Souza BarrosLaboratório de Virologia Molecular e Biotecnologia Marinha, Programa de Pós-graduação em Ciências e Biotecnologia, Departamento de Biologia Celular e Molecular, Instituto de Biologia, Universidade Federal Fluminense, Niterói, Brazil.
Caio Cesar Richter NogueiraLaboratório de Virologia Molecular e Biotecnologia Marinha, Programa de Pós-graduação em Ciências e Biotecnologia, Departamento de Biologia Celular e Molecular, Instituto de Biologia, Universidade Federal Fluminense, Niterói, Brazil.
Renata Campos AzevedoInstituto de Microbiologia Paulo de Góes (IMPPG), Departamento de Virologia, Universidade Federal do Rio de Janeiro, Rio de Janeiro, Brazil.
Kristie Aimi YamamotoInstituto de Microbiologia Paulo de Góes (IMPPG), Departamento de Virologia, Universidade Federal do Rio de Janeiro, Rio de Janeiro, Brazil.
Guilherme Louzada Silva MeiraInstituto de Microbiologia Paulo de Góes (IMPPG), Departamento de Virologia, Universidade Federal do Rio de Janeiro, Rio de Janeiro, Brazil.
Zilton Farias Meira de VasconcelosInstituto Fernandes Figueira (IFF), Fundação Oswaldo Cruz (Fiocruz), Rio de Janeiro, Brazil.
Norman Arthur RatcliffeDepartment of Biosciences, College of Science, Swansea University, Swansea, United Kingdom.
Valéria Laneuville TeixeiraLaboratório de Produtos Naturais de Algas Marinhas (ALGAMAR), Departamento de Biologia Marinha, Instituto de Biologia, Universidade Federal Fluminense, Niterói, Brazil.
Jonas Schmidt-ChanasitBernhard Nocht Institute for Tropical Medicine, WHO Collaborating Centre for Arbovirus and Haemorrhagic Fever Reference and Research, Hamburg, Germany.
Davis Fernandes FerreiraInstituto de Microbiologia Paulo de Góes (IMPPG), Departamento de Virologia, Universidade Federal do Rio de Janeiro, Rio de Janeiro, Brazil.
Izabel Christina Nunes de Palmer PaixãoLaboratório de Virologia Molecular e Biotecnologia Marinha, Programa de Pós-graduação em Ciências e Biotecnologia, Departamento de Biologia Celular e Molecular, Instituto de Biologia, Universidade Federal Fluminense, Niterói, Brazil.
Universidade Federal Fluminense · BRUniversidade Federal do Rio de Janeiro · BRBernhard Nocht Institute for Tropical Medicine · DEFundação Oswaldo Cruz · BRNorth Carolina State University · USSwansea University · GBUniversidade Salgado de Oliveira · BR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Chikungunya virus (CHIKV) infection is one of the most challenging re-emergent diseases caused by a virus, and with no specific antiviral treatment it has now become a major public health concern. In this investigation, 25 blood samples were collected from patients with characteristic CHIKV symptoms and submitted to a virus isolation protocol, which detected 3 CHIKV isolates. These samples were evaluated by sequencing for the characterization of the strains and any homology to viruses circulating in Brazil during a recent outbreak. These viruses were used for the development of antiviral assays. Subsequently, the inhibitory effects of seaweed extracts on CHIKV replication were studied. The marine species of algae tested were

Indexed as

antiviralarboviruschikungunyacrude extractsseaweed

Identifiers

PMID31708898
PMCPMC6821653
OpenAlexW2981411323

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.