Evidence map›Paper›PMID 31708749›Full record

ArticleFrontiers in cellular neuroscience2019

Orexin-A Excites Airway Vagal Preganglionic Neurons

Yonghua Chen, Yuhong Guo, Xianxia Yan, Ming Zeng, Hong Chen, Dongying Qiu, Jijiang Wang

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Frontiers in cellular neuroscience, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.1field-weighted citation impact, top 51% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 3 citations in OpenAlex.

  1. Endothelin-1-mediated Brainstem Glial Activation Produces Asthmatic Airway Vagal Hypertonia Via Enhanced ATP-P2X4 Receptor Signaling in Sprague-Dawley Rats.Journal of neuroimmune pharmacology : the official journal of the Society on NeuroImmune Pharmacology · 2024
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Yonghua ChenDepartment of Physiology and Pathophysiology, School of Basic Medical Sciences, Fudan University, Shanghai, China.
Yuhong GuoDepartment of Neurobiology, School of Basic Medical Sciences, Fudan University, Shanghai, China.
Xianxia YanDepartment of Neurobiology, School of Basic Medical Sciences, Fudan University, Shanghai, China.
Ming ZengDepartment of Physiology and Pathophysiology, School of Basic Medical Sciences, Fudan University, Shanghai, China.
Hong ChenDepartment of Physiology and Pathophysiology, School of Basic Medical Sciences, Fudan University, Shanghai, China.
Dongying QiuDepartment of Gerontology, Fudan University Affiliated Zhongshan Hospital, Shanghai, China.
Jijiang WangDepartment of Physiology and Pathophysiology, School of Basic Medical Sciences, Fudan University, Shanghai, China.
Fudan University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Airway vagal nerves play a predominant role in the neural control of the airway, and augmented airway vagal activity is known to play important roles in the pathogenesis of some chronic inflammatory airway diseases. Several lines of evidence indicate that dysfunctional central orexinergic system is closely related to the severity of airway diseases, however, whether orexins affect airway vagal activity is unknown. This study investigates whether and how orexin-A regulates the activity of medullary airway vagal preganglionic neurons (AVPNs). The expression of orexin receptor type 1 (OX

Indexed as

airway resistanceorexinpreganglionic neuronsynaptic transmissionvagus nerve

Identifiers

PMID31708749
PMCPMC6819310
OpenAlexW2981361708

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.