Evidence map›Paper›PMID 31708408›Full record

ReviewTrends in cardiovascular medicine2020

New approaches for treating atrial fibrillation: Focus on autonomic modulation.

Daniel Sohinki, Stavros Stavrakis

Abstract readReview
In one paragraph

Review in Trends in cardiovascular medicine, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Article
  4. Review
  5. Article
  6. Review
  7. The role of electrical stimulation for rehabilitation and regeneration after spinal cord injury.Journal of orthopaedics and traumatology : official journal of the Italian Society of Orthopaedics and Traumatology · 2022
    Review
  8. Article
  9. Neuromodulation Therapy in Heart Failure: Combined Use of Drugs and Devices.The Journal of innovations in cardiac rhythm management · 2020
    Article
  10. Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

2 authors.

Daniel SohinkiDepartment of Cardiology, Augusta University Medical Center, Augusta, GA, United States.
Stavros StavrakisDepartment of Cardiology, University of Oklahoma Health Sciences Center, 800 Stanton L. Young Blvd., Suite 5400, Oklahoma, OK, United States; Heart Rhythm Institute, University of Oklahoma Health Sciences Center, Oklahoma, OK, United States. Electronic address: stavros-stavrakis@ouhsc.edu.

Funding

Proteomics CoreP20GM103447 · NIGMS · UNIVERSITY OF OKLAHOMA HLTH SCIENCES CTR · PI Mark L Lang · 2012 to 2026
$60.2M
Addressing Health Disparities among Oklahoma Minority and Rural Communities through Clinical Research Education and Career DevelopmentR25MD011564 · NIMHD · UNIVERSITY OF OKLAHOMA HLTH SCIENCES CTR · PI HOUCHEN, COURTNEY WAYNE, STAVRAKIS, STAVROS · 2017 to 2021
$2.7M
Neuromodulation of Inflammation to Treat Heart Failure with Preserved Ejection FractionR21AG057879 · NIA · UNIVERSITY OF OKLAHOMA HLTH SCIENCES CTR · PI STAVRAKIS, STAVROS · 2018 to 2019
$407k
NIA NIH HHS R21 AG057879NIGMS NIH HHS P20 GM103447NIMHD NIH HHS R25 MD011564
6 · The paper itself

Abstract

Atrial fibrillation (AF) is a rapidly growing clinical problem in routine practice, both for cardiologists as well as general practitioners. Current therapies aimed at the management of AF include anti-arrhythmic drug therapy and catheter ablation. These therapies have a number of limitations and risks, and have disappointing long-term efficacy in maintaining sinus rhythm and improving hard clinical outcomes. Because of this, there is growing interest in pursuing alternative management strategies in patients with AF. This review seeks to highlight emerging AF therapies, with a specific focus on several modalities aimed at modulation of the autonomic nervous system. These therapies have shown promise in early pre-clinical and clinical trials, and represent exciting alternatives to standard AF treatment.

Indexed as

Heart RateMagnetic Field TherapySympathectomyVagus Nerve StimulationAnimalsAtrial FibrillationAutonomic Nervous SystemBaroreflexHeart AtriaHumansKidneyPressoreceptorsRecovery of FunctionRenal ArteryTreatment OutcomeAtrial fibrillationAutonomic modulation

Identifiers

PMID31708408
PMCPMC7190441

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.