ArticleJournal of biomechanics2020
Age-associated changes in the mechanical properties of human cadaveric pelvic floor muscles.
Article in Journal of biomechanics, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
24 citing papers in PubMed, 1 synthesis or guideline pooled it, 34 citations in OpenAlex.
- Systematic review of skeletal muscle passive mechanics experimental methodology.Journal of biomechanics · 2021Pooled it
- Pelvic Floor Knowledge and Dysfunctions in Female Athletes: Impact of Demographics, Sport Profile, and Physical Activity.International urogynecology journal · 2026Article
- Female pelvic floor protection-Where do we have to go?Acta obstetricia et gynecologica Scandinavica · 2026Review
- Passive Mechanical Testing of Female Human Levator Ani and Superficial Perineal Muscles.Annals of biomedical engineering · 2026Article
- Noninvasive assessment of oxidative stress in pelvic organ prolapse: a feasibility study.Scientific reports · 2025Article
- Structured and supervised pelvic floor muscle training following confirmed contraction in post-prostatectomy urinary incontinence: a systematic review of randomized controlled trials.Journal of cancer survivorship : research and practice · 2025Review
- Hiatus and pelvic floor failure patterns in pelvic organ prolapse: a 3D MRI study of structural interactions using a level III conceptual model.American journal of obstetrics and gynecology · 2025Article
- Are pelvic floor muscle function, quadriceps femoris muscle, gluteus medius muscle, hand grip strength and functional performance affected by incontinence types in elderly people with urinary incontinence?International urology and nephrology · 2025Article
- Pelvic Floor Muscle Evaluation in Older Women with Urinary Incontinence: A Feasibility Study.International urogynecology journal · 2024Article
- A unified pelvic floor conceptual model for studying morphological changes with prolapse, age, and parity.American journal of obstetrics and gynecology · 2024Review
- Screening for Incidence and Effect of Pelvic Floor Dysfunction in College-Aged Athletes.International journal of sports physical therapy · 2024Article
- Analysis of questions by patients with pelvic organ prolapse about vaginal pessaries resulting in a checklist for their physicians.Archives of gynecology and obstetrics · 2024Article
- Article
- Article
- A comparison of MRI-based pelvic floor support measures between young and old women with prolapse.International urogynecology journal · 2023Article
- Skeletal muscle aging and sarcopenia: Perspectives from mechanical studies of single permeabilized muscle fibers.Journal of biomechanics · 2023Review
- International Urogynecological Consultation (IUC): pathophysiology of pelvic organ prolapse (POP).International urogynecology journal · 2022Review
- Foundational science and mechanistic insights for a shared disease model: an expert consensus : Developed by the AUGS Basic Science Subcommittee and IUGA Special Interest Group.International urogynecology journal · 2022Article
- Foundational Science and Mechanistic Insights for a Shared Disease Model: An Expert Consensus.Female pelvic medicine & reconstructive surgery · 2022Article
- Biaxial Murine Vaginal Remodeling With Reproductive Aging.Journal of biomechanical engineering · 2022Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors at 2 institutions in 1 country.
Funding
Abstract
Proper function of the female pelvic floor requires intact pelvic floor muscles (PFMs). The prevalence of pelvic floor disorders (PFDs) increases substantially with age, in part due to clinically identified deterioration of PFM function with age. However, the etiology of this decline remains largely unknown. We previously demonstrated that PFMs undergo age-related fibrotic changes. This study sought to determine whether aging also impacts PFMs' passive mechanical properties that are largely determined by the intramuscular extracellular matrix. Biopsies from younger (≤52y) and older (>52y) female cadaveric donors were procured from PFMs, specifically coccygeus (C) and two portions of the levator ani - iliococcygeus (IC) and pubovisceralis (PV), and the appendicular muscles - obturator internus (OI) and vastus lateralis (VL). Muscle bundles were subjected to a passive loading protocol, and stress-sarcomere length (L
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.