Evidence map›Paper›PMID 31708161›Full record

ArticleBiophysical journal2019

Regulation of Nearest-Neighbor Cooperative Binding of E. coli SSB Protein to DNA.

Alexander G Kozlov, Min Kyung Shinn, Timothy M Lohman

Open access · bronzeAbstract read
In one paragraph

Article in Biophysical journal, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
1.5field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 27 citations in OpenAlex.

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  8. Cooperative kinetics of ligand binding to linear polymers.Computational and structural biotechnology journal · 2022
    Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Phase separation by ssDNA binding protein controlled via protein-protein and protein-DNA interactions.Proceedings of the National Academy of Sciences of the United States of America · 2020
    Article
  14. Article
  15. Article
  16. Molecular insights into the prototypical single-stranded DNA-binding protein fromCritical reviews in biochemistry and molecular biology
    Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Alexander G KozlovDepartment of Biochemistry and Molecular Biophysics, Washington University School of Medicine, St. Louis, Missouri.
Min Kyung ShinnDepartment of Biochemistry and Molecular Biophysics, Washington University School of Medicine, St. Louis, Missouri; Department of Physics, Washington University in St. Louis, St. Louis, Missouri.
Timothy M LohmanDepartment of Biochemistry and Molecular Biophysics, Washington University School of Medicine, St. Louis, Missouri. Electronic address: lohman@wustl.edu.
Washington University in St. Louis · US

Funding

SSB PROTEIN/DNA INTERACTIONSR01GM030498 · NIGMS · WASHINGTON UNIVERSITY · PI LOHMAN, TIMOTHY M · 1985 to 2019
$7.4M
NIGMS NIH HHS R01 GM030498
6 · The paper itself

Abstract

Escherichia coli single-strand (ss) DNA-binding protein (SSB) is an essential protein that binds ssDNA intermediates formed during genome maintenance. SSB homotetramers bind ssDNA in several modes differing in occluded site size and cooperativity. The 35-site-size ((SSB)

Indexed as

DNA-Binding ProteinsDNA, Single-StrandedEscherichia coli ProteinsModels, MolecularOligodeoxyribonucleotidesProtein BindingProtein ConformationDNA-Binding ProteinsDNA, Single-StrandedEscherichia coli ProteinsOligodeoxyribonucleotidesoligo (dT)SSB protein, E coli

Identifiers

PMID31708161
PMCPMC6895745
OpenAlexW2982587873

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.