ArticleJournal of enzyme inhibition and medicinal chemistry2020
Discovery and evaluation of novel synthetic 5-alkyl-4-oxo-4,5-dihydro-[1,2,4]triazolo[4,3-a]quinoxaline-1-carbox-amide derivatives as anti-inflammatory agents.
Article in Journal of enzyme inhibition and medicinal chemistry, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
6 citing papers in PubMed, 29 citations in OpenAlex.
- Synthesis and Biological Activity of Azolo[Molecules (Basel, Switzerland) · 2026Review
- Synthetic Methods of Quinoxaline Derivatives and their Potential Anti-inflammatory Properties.Mini reviews in medicinal chemistry · 2025Review
- [1,2,4]triazolo[4,3-Molecules (Basel, Switzerland) · 2023Article
- A possible potential COVID-19 drug candidate: Diethyl 2-(2-(2-(3-methyl-2-oxoquinoxalin-1(2H)-yl)acetyl)hydrazono)malonate: Docking of disordered independent molecules of a novel crystal structure, HSA/DFT/XRD and cytotoxicity.Arabian journal of chemistry · 2022Article
- Facile synthesis, spectroscopic evaluation and antimicrobial screening of metal endowed triazole compounds.Biometals : an international journal on the role of metal ions in biology, biochemistry, and medicine · 2021Article
- Small molecule compounds with good anti-inflammatory activity reported in the literature from 01/2009 to 05/2021: a review.Journal of enzyme inhibition and medicinal chemistry · 2021Review
Corrections and comments
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Authors and funding
6 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
To develop novel anti-inflammatory agents, a series of 5-alkyl-4-oxo-4,5-dihydro-[1, 2, 4]triazolo[4,3-a]quinoxaline-1-carboxamide derivatives were designed, synthesised, and evaluated for anti-inflammatory effects using RAW264.7 cells. Structures of the synthesised compounds were determined using
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.