Evidence map›Paper›PMID 31707624›Full record

ReviewReviews in endocrine & metabolic disorders2019

Dietary lipids, gut microbiota and lipid metabolism.

Marc Schoeler, Robert Caesar

Open access · hybridAbstract readReview
In one paragraph

Review in Reviews in endocrine & metabolic disorders, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 640 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
640citing papers in PubMed, 3 pooled it
48.9field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

640 citing papers in PubMed, 3 syntheses or guidelines pooled it, 1,110 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Pooled it
  4. Trial
  5. Effect ofNutrients · 2026
    Trial
  6. Abnormal "Frontiers in cardiovascular medicine · 2026
    Trial
  7. Trial
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  9. Effect of DailyMedicina (Kaunas, Lithuania) · 2025
    Trial
  10. Review
  11. Article
  12. Gut microbial alterations and functional shifts in patients with hypertriglyceridemia: insights from a northwestern Chinese metagenomic study.International microbiology : the official journal of the Spanish Society for Microbiology · 2026
    Article
  13. Review
  14. Article
  15. Furong Tongmai Capsule Ameliorates Atherosclerosis in ApoEJournal of cellular and molecular medicine · 2026
    Article
  16. Article
  17. Review
  18. Article
  19. Review
  20. Review

580 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Marc SchoelerThe Wallenberg Laboratory, Department of Molecular and Clinical Medicine, University of Gothenburg, 41345, Gothenburg, Sweden.
Robert CaesarThe Wallenberg Laboratory, Department of Molecular and Clinical Medicine, University of Gothenburg, 41345, Gothenburg, Sweden. robert.caesar@wlab.gu.se.ORCID 0000-0003-1017-2933
University of Gothenburg · SE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The gut microbiota is a central regulator of host metabolism. The composition and function of the gut microbiota is dynamic and affected by diet properties such as the amount and composition of lipids. Hence, dietary lipids may influence host physiology through interaction with the gut microbiota. Lipids affect the gut microbiota both as substrates for bacterial metabolic processes, and by inhibiting bacterial growth by toxic influence. The gut microbiota has been shown to affect lipid metabolism and lipid levels in blood and tissues, both in mice and humans. Furthermore, diseases linked to dyslipidemia, such as non-alcoholic liver disease and atherosclerosis, are associated with changes in gut microbiota profile. The influence of the gut microbiota on host lipid metabolism may be mediated through metabolites produced by the gut microbiota such as short-chain fatty acids, secondary bile acids and trimethylamine and by pro-inflammatory bacterially derived factors such as lipopolysaccharide. Here we will review the association between gut microbiota, dietary lipids and lipid metabolism.

Indexed as

AnimalsBile Acids and SaltsGastrointestinal MicrobiomeHumansLipid MetabolismLipidsMethylaminesBile Acids and SaltsLipidsMethylaminestrimethylamineAtherosclerosisBile acidDietDietary lipidDysbiosisDyslipidemiaFatty acidFXRGut microbiotaGut permeabilityInflammationLipidLipid metabolismLipopolysaccharidesLPSMicrobiomeNAFLDNon-alcoholic liver diseaseTGR5TMATMAOTrimethylamine N-oxide

Identifiers

PMID31707624
PMCPMC6938793
OpenAlexW2984669963

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.