Evidence map›Paper›PMID 31707065›Full record

ArticleThe journal of allergy and clinical immunology. In practice2020

Real-World Assessment of Asthma Control and Severity in Children, Adolescents, and Adults with Asthma: Relationships to Care Settings and Comorbidities.

Sharmilee M Nyenhuis, Esra Akkoyun, Li Liu, Michael Schatz, Thomas B Casale

Open access · greenAbstract read
In one paragraph

Article in The journal of allergy and clinical immunology. In practice, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
2.3field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 29 citations in OpenAlex.

  1. Review
  2. Article
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  4. Article
  5. Epidemiology of Childhood Asthma in the UK.Journal of asthma and allergy · 2024
    Article
  6. Article
  7. Article
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  9. Article
  10. Positive associations of pollutants and aeroallergens with allergic rhinitis in adults with asthma.Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology · 2022
    Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. Asthma and stroke: a narrative review.Asthma research and practice · 2021
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 1 country.

Sharmilee M NyenhuisDivision of Pulmonary, Critical Care, Sleep and Allergy, Department of Medicine, University of Illinois at Chicago, Chicago, Ill; Center for Dissemination and Implementation Science, Department of Medicine, University of Illinois at Chicago, Chicago, Ill. Electronic address: snyenhui@uic.edu.
Esra AkkoyunDivision of Pulmonary, Critical Care, Sleep and Allergy, Department of Medicine, University of Illinois at Chicago, Chicago, Ill.
Li LiuDivision of Epidemiology and Biostatistics, School of Public Health, University of Illinois at Chicago, Chicago, Ill.
Michael SchatzAllergy Department, Kaiser Permanente, San Diego, Calif.
Thomas B CasaleDepartment of Internal Medicine, University of South Florida, Tampa, Fla.
University of Illinois Chicago · USKaiser Permanente · USUniversity of South Florida · US

Funding

Strengthening Stakeholder Engagement in Human Research Protections.UL1TR002003 · NCATS · UNIVERSITY OF ILLINOIS AT CHICAGO · PI KARNIK, NIRANJAN SUBHASH, MERMELSTEIN, ROBIN J. · 2016 to 2024
$33.7M
Center for Clinical and Translational ScienceKL2RR029878 · NCRR · UNIVERSITY OF ILLINOIS AT CHICAGO · PI TOBACMAN, LARRY S · 2009 to 2011
$988k
ACTION Intervention: Physical Activity in Minority Women with AsthmaK01HL133370 · NHLBI · UNIVERSITY OF ILLINOIS AT CHICAGO · PI NYENHUIS, SHARMILEE MARIA · 2016 to 2019
$741k
NCATS NIH HHS UL1 TR002003NCRR NIH HHS KL2 RR029878NHLBI NIH HHS K01 HL133370
6 · The paper itself

Abstract

backgroundLittle is known about how patient-level factors and care settings relate to asthma outcomes in real-world settings.

objectiveWe therefore examined the rates and relative contributions of comorbidities and care settings in terms of asthma severity and control among pediatric and adolescent/adult patients in a large national sample.

methodsWe examined deidentified patient data from 28,508 unique encounters documented in the Asthma Specialist Tool to Help Manage Asthma and Improve Quality database, obtaining patient-level factors (demographics, asthma characteristics, comorbidities), care setting (primary care physician [PCP] vs specialist physician [allergist or pulmonologist]), and guideline-defined levels of asthma control/severity. Rates of comorbidities were identified by asthma severity and control and by care setting. We calculated odds ratios for asthma control and severity based on each comorbidity.

resultsBaseline demographic data indicated that patients seen by specialists versus PCPs were older, and had more severe and poorly controlled asthma (P < .05). Patients cared for by specialists also had more comorbid conditions, including gastroesophageal reflux disease (GERD; P < .01), rhinosinusitis (P < .01), and obstructive sleep apnea (adolescents/adults only: P < .01). GERD, smoke exposure, depression (adolescents/adults), rhinosinusitis (children), and African American race were associated with uncontrolled asthma. Smoke exposure (children), rhinosinusitis, and African American race were associated with severe disease.

conclusionsWe identified several demographics and comorbidities that are independently associated with the specialist care setting, persistent asthma, and poor asthma control. Awareness of these relationships may be helpful for clinicians caring for patients with asthma.

Indexed as

AsthmaGastroesophageal RefluxSleep Apnea, ObstructiveAdolescentAdultChildComorbidityHumansAsthmaComorbidityComputer-assistedMedical decision makingPractice guideline

Identifiers

PMID31707065
PMCPMC7064399
OpenAlexW2994446545

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.