Evidence map›Paper›PMID 31706841›Full record

ReviewTrends in molecular medicine2020

Visualizing Mitochondrial Form and Function within the Cell.

Brian Glancy

Abstract readReview
In one paragraph

Review in Trends in molecular medicine, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 49 papers.

0numbers the graph read from it
0cells of the map it votes in
49citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

49 citing papers in PubMed.

  1. Article
  2. Combatting pulmonary fibrosis withChinese herbal medicines · 2026
    Review
  3. Article
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  16. Review
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  18. Review
  19. The bioenergetic landscape of cancer.Molecular metabolism · 2024
    Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

1 author.

Brian GlancyNational Heart, Lung, and Blood Institute, National Institutes of Health, Bethesda, MD, USA; National Institute of Arthritis and Musculoskeletal and Skin Diseases, National Institutes of Health, Bethesda, MD, USA. Electronic address: brian.glancy@nih.gov.

Funding

Development and Regulation of the Muscle Mitochondrial ReticulumZIAHL006221 · NHLBI · NATIONAL HEART, LUNG, AND BLOOD INSTITUTE · PI GLANCY, BRIAN · 2017 to 2025
$14.7M
Intramural NIH HHS ZIA HL006221
6 · The paper itself

Abstract

The specific cellular role of mitochondria is influenced by the surrounding environment because effective mitochondrial function requires the delivery of inputs (e.g., oxygen) and export of products (e.g., signaling molecules) to and from other cellular components, respectively. Recent technological developments in mitochondrial imaging have led to a more precise and comprehensive understanding of the spatial relationships governing the function of this complex organelle, opening a new era of mitochondrial research. Here, I highlight current imaging approaches for visualizing mitochondrial form and function within complex cellular environments. Increasing clarity of mitochondrial behavior within cells will continue to lend mechanistic insights into the role of mitochondria under normal and pathological conditions and point to spatially regulated processes that can be targeted to improve cellular function.

Indexed as

AnimalsHumansMitochondriaOrganelle BiogenesisOxygenSignal TransductionOxygen3D electron microscopyEnergy metabolismsuper-resolution microscopysystems-level imaging

Identifiers

PMID31706841
PMCPMC6938546

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.