Evidence map›Paper›PMID 31706711›Full record

ArticleDrug and alcohol dependence2019

Alcohol use in late adolescence and early adulthood: The role of generalized anxiety disorder and drinking to cope motives.

Maddy L Dyer, Jon Heron, Matthew Hickman, Marcus R Munafò

Abstract read
In one paragraph

Article in Drug and alcohol dependence, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed.

  1. An adolescent hangover: astrocyte dysfunction in paraventricular thalamus promotes adult anxiety after alcohol exposure in adolescent mice.Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology · 2026
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  7. Modeling momentary reciprocal associations between negative affect and craving for alcohol and cannabis using dynamic structural equation modeling.Psychology of addictive behaviors : journal of the Society of Psychologists in Addictive Behaviors · 2024
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Maddy L DyerSchool of Psychological Science, University of Bristol, Bristol, United Kingdom; Population Health Sciences, Bristol Medical School, University of Bristol, Bristol, United Kingdom; MRC Integrative Epidemiology Unit (IEU), University of Bristol, Bristol, United Kingdom. Electronic address: maddy.dyer@bristol.ac.uk.
Jon HeronPopulation Health Sciences, Bristol Medical School, University of Bristol, Bristol, United Kingdom; MRC Integrative Epidemiology Unit (IEU), University of Bristol, Bristol, United Kingdom. Electronic address: jon.heron@bristol.ac.uk.
Matthew HickmanPopulation Health Sciences, Bristol Medical School, University of Bristol, Bristol, United Kingdom; MRC Integrative Epidemiology Unit (IEU), University of Bristol, Bristol, United Kingdom. Electronic address: matthew.hickman@bristol.ac.uk.
Marcus R MunafòSchool of Psychological Science, University of Bristol, Bristol, United Kingdom; MRC Integrative Epidemiology Unit (IEU), University of Bristol, Bristol, United Kingdom. Electronic address: marcus.munafo@bristol.ac.uk.

Funding

British Heart FoundationCancer Research UKDepartment of HealthMedical Research Council G0800612Medical Research Council G0802736Medical Research Council G9815508Medical Research Council MC_PC_15018Medical Research Council MC_PC_19009Medical Research Council MC_UU_00011/7Medical Research Council MR/KO232331/1Medical Research Council MR/L022206/1Wellcome Trust
6 · The paper itself

Abstract

backgroundThe relationship between anxiety and alcohol use is unclear, and moderating factors, such as drinking to cope (DTC) motives, may explain mixed findings.

methodsUsing the Avon Longitudinal Study of Parents and Children (ALSPAC), we examined associations between generalized anxiety disorder (GAD) at age 18 and frequent drinking, frequent bingeing, hazardous drinking, and harmful drinking at ages 18 (unadjusted n = 3462) and 21 (unadjusted n = 2076), in a sample of late adolescent drinkers. Analyses were adjusted for sociodemographic, parental, and adolescent confounders. We also examined whether DTC motives influenced the strength and direction of associations between GAD and alcohol use.

resultsGAD was positively associated with all alcohol outcomes at baseline (unadjusted OR (95% CI): frequent drinking 1.40 (1.02-1.91); frequent bingeing 1.40 (0.96-2.04); hazardous drinking 1.44 (1.08-1.92); harmful drinking 1.98 (1.22-3.23)). GAD increased the odds of harmful drinking at age 21 (unadjusted OR 1.72, 95% CI 1.09-2.73), but there was no clear evidence of a longitudinal relationship between GAD and the other alcohol use outcomes. There was no clear evidence of a GAD x DTC interaction on alcohol use at ages 18 or 21. Findings were consistent across various multiply imputed datasets.

conclusionsIn adolescence, GAD symptoms are associated with frequent drinking, frequent bingeing, hazardous drinking, and harmful drinking. In early adulthood, associations remain for harmful drinking only. DTC motives do not appear to moderate the relationship at either age.

Indexed as

Adaptation, PsychologicalMotivationAdolescentAlcohol DrinkingAnxiety DisordersFemaleHumansLongitudinal StudiesMaleUnderage DrinkingYoung AdultAlcoholALSPACDrinking-To-CopeGeneralized anxiety disorderLongitudinal

Identifiers

PMID31706711
PMCPMC6891250

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.