ArticleAIDS research and therapy2019
Syndemic factors associated with adherence to antiretroviral therapy among HIV-positive adult heterosexual men.
Article in AIDS research and therapy, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers, 1 of them a synthesis that pooled it.
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Who cites it
28 citing papers in PubMed, 1 synthesis or guideline pooled it, 50 citations in OpenAlex.
- Syndemics and clinical impact of HIV and mental health conditions among people living with HIV: a systematic review and meta-analysis.Frontiers in public health · 2026Pooled it
- A US-Based National Virtual Cohort of People Living With HIV at Risk for Viral Nonsuppression: Protocol for the EPI-LoVE Prospective Cohort Study.JMIR research protocols · 2026Article
- Clinical outcomes after the implementation of a patient-centered care program applied to newly admitted people with HIV in Mexico City: a retrospective cohort study.AIDS research and therapy · 2026Article
- The Impact of Childhood Household Violence on HIV-Related Outcomes in People With HIV in the United States: The Role of Psychological Distress and Social Stressors.Journal of acquired immune deficiency syndromes (1999) · 2026Article
- Article
- The impact of Undetectable=Untransmittable and viral suppression on condomless sex among mixed HIV-status couples in Canada.PloS one · 2025Article
- A Review of Implementation Strategies to Enhance PrEP Delivery for People Experiencing Housing Insecurity: Advancing a Multifaceted High-Touch, Low-Barrier Approach.Current HIV/AIDS reports · 2024Review
- Analyzing Social Support from Facebook on Viral Suppression among Young Black Men Who Have Sex with Men Living with HIV: A Pilot Study.International journal of environmental research and public health · 2024Article
- Comorbidity Burden and Health Care Utilization by Substance use Disorder Patterns among People with HIV in Florida.AIDS and behavior · 2024Article
- Piloting Siyakhana: A community health worker training to reduce substance use and depression stigma in South African HIV and TB care.PLOS global public health · 2024Article
- Immune reconstitution efficacy after combination antiretroviral therapy in male HIV-1 infected patients with homosexual and heterosexual transmission.Emerging microbes & infections · 2023Article
- High Psychosocial Burden Relates to Poorer Antiretroviral Treatment Adherence Among Black/African American People with HIV.AIDS patient care and STDs · 2023Article
- Psychosocial risk factors of erectile dysfunction among heterosexual men living with HIV.AIDS care · 2023Article
- A qualitative inquiry of experiences of HIV-related stigma and its effects among people living with HIV on treatment in rural Kilifi, Kenya.Frontiers in public health · 2023Article
- Article
- The converging influence of social, economic and psychological factors on public responsiveness to the COVID-19 pandemic in South Africa.BMC public health · 2022Article
- Neurocognitive decline as a major predictor of nonadherence to antiretroviral therapy among adults living with HIV in Dodoma region, central Tanzania.Health science reports · 2022Article
- Article
- HIV-serodifferent couples' perspectives and practices regarding HIV prevention strategies: A mixed methods study.PLOS global public health · 2022Article
- Patient-Reported Experiences of Medication Adherence at a Community-Based HIV Clinic, Ghana.Journal of patient experience · 2022Article
Corrections and comments
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Authors and funding
7 authors at 3 institutions in 1 country.
Funding
Abstract
backgroundSuboptimal adherence to HIV antiretroviral therapy (ART) and concomitant lack of viral control can have severe consequences for health and onward transmission among persons living with HIV. Little is known about the barriers and facilitators of optimal ART adherence among heterosexual HIV-positive men.
methodsStructural equation modeling (SEM) was performed to test a theory-derived model of ART adherence using data from a cross-sectional sample of 317 HIV-positive self-identified heterosexual men residing in New York City. We assessed a conceptual model in which mental health (depression, anxiety) and substance use dependence mediated the effects of socio-structural factors (HIV-related stigma, social support) on ART adherence, and subsequently, undetectable viral load.
resultsStructural equation modeling analyses indicated that men who reported higher levels of HIV-related stigma tended to experience higher levels of general anxiety, which in turn was associated with reduced probability of optimal ART adherence. Moreover, men who reported higher levels of social support tended to exhibit less dependence on illicit substance use, which in turn was associated with increased probability of optimal ART adherence. African-American men reported lower ART adherence compared to other racial/ethnic groups.
conclusionsOur findings support the hypothesis that substance use dependence and mental health problems, particularly anxiety, may be primary drivers of suboptimal ART adherence among heterosexual men, and that socio-structural factors such as HIV-related stigma and social support are potential modifiable antecedents of these drivers.
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