Evidence map›Paper›PMID 31706292›Full record

Trial reportBMC neurology2019

Gothenburg Very Early Supported Discharge study (GOTVED): a randomised controlled trial investigating anxiety and overall disability in the first year after stroke.

Lena Rafsten, Anna Danielsson, Asa Nordin, Ann Björkdahl, Asa Lundgren-Nilsson, Maria E H Larsson, Katharina S Sunnerhagen

Registry-linked trialAbstract readRandomized Controlled Trial
PubMed Full text at PMC Publisher
In one paragraph

Trial report in BMC neurology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT01622205 (Phase 2 Study of Very Early Supported Discharge From a Stroke Unit in), which is not on this map. Cited by 17 papers, 5 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed, 5 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT01622205 phase2completednot on this map

Phase 2 Study of Very Early Supported Discharge From a Stroke Unit in

TypeinterventionalSponsorGöteborg UniversityRan2011 to 2019Enrolled140ConditionsStrokeArmsVery early supported discharge (VESD), Ordinary rehabilitation
3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 5 syntheses or guidelines pooled it.

  1. Integrated care management for patients following acute stroke: a systematic review.QJM : monthly journal of the Association of Physicians · 2025
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  9. Early Occupational Therapy Intervention in the Hospital Discharge after Stroke.International journal of environmental research and public health · 2021
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Lena RafstenInstitute of Neuroscience and Physiology, Department of Clinical Neuroscience and Rehabilitation Medicine, Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden. Per Dubbsgatan 14, fl. 3, 413 45, Gothenburg, Sweden. lena.rafsten@vgregion.se.ORCID http://orcid.org/0000-0002-2226-6227
Anna DanielssonInstitute of Neuroscience and Physiology, Department of Clinical Neuroscience and Rehabilitation Medicine, Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden. Per Dubbsgatan 14, fl. 3, 413 45, Gothenburg, Sweden.
Asa NordinInstitute of Neuroscience and Physiology, Department of Clinical Neuroscience and Rehabilitation Medicine, Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden. Per Dubbsgatan 14, fl. 3, 413 45, Gothenburg, Sweden.
Ann BjörkdahlInstitute of Neuroscience and Physiology, Department of Clinical Neuroscience and Rehabilitation Medicine, Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden. Per Dubbsgatan 14, fl. 3, 413 45, Gothenburg, Sweden.
Asa Lundgren-NilssonInstitute of Neuroscience and Physiology, Department of Clinical Neuroscience and Rehabilitation Medicine, Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden. Per Dubbsgatan 14, fl. 3, 413 45, Gothenburg, Sweden.
Maria E H LarssonInstitute of Neuroscience and Physiology, Department of Health and Rehabilitation, Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden.
Katharina S SunnerhagenInstitute of Neuroscience and Physiology, Department of Clinical Neuroscience and Rehabilitation Medicine, Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden. Per Dubbsgatan 14, fl. 3, 413 45, Gothenburg, Sweden.

Funding

Swedish Science Council VR2012-3523
6 · The paper itself

Abstract

background and purposeEarly supported discharge (ESD) has been shown to be efficient and safe as part of the stroke care pathway. The best results have been seen with a multidisciplinary team and after mild to moderate stroke. However, how very early supported discharge (VESD) works has not been studied. The aim of this study was to investigate whether VESD for stroke patients in need of ongoing individualized rehabilitation affects the level of anxiety and overall disability for the patient compared with ordinary discharge routine.

methodsA randomized controlled trial was performed with intention to treat analyses comparing VESD and ordinary discharge from hospital. All patients admitted at the stroke care unit at Sahlgrenska University Hospital of Gothenburg between August 2011 and April 2016 were screened. Inclusion occurred on day 4 using a block randomization of 20 and with a blinded assessor. Assessments were made 5 days post-stroke and 3 and 12 months post-stroke. Patients in the VESD group underwent continued rehabilitation in their homes with a multidisciplinary team from the stroke care unit for a maximum of 1 month. The patients in the control group had support as usual after discharge when needed such as home care service and outpatient rehabilitation. The primary outcome was anxiety as assessed by the Hospital Anxiety and Depression Scale-Anxiety subscale (HADS-A). The secondary outcome was the patients' degree of overall disability, measured by the modified Rankin Scale (mRS).

resultsNo significant differences were found between the groups regarding anxiety at three or 12 months post-stroke (p = 0.811). The overall disability was significantly lower in the VESD group 3 months post-stroke (p = 0.004), compared to the control group. However, there was no significant difference between the groups 1 year post-stroke.

conclusionsThe VESD does not affects the level of anxiety compared to ordinary rehabilitation. The VESD leads to a faster improvement of overall disability compared to ordinary rehabilitation. We suggest considering coordinated VESD for patients with mild to moderate stroke in addition to ordinary rehabilitation as part of the service from a stroke unit.

trial registrationClinical Trials.gov: NCT01622205. Registered 19 June 2012 (retrospectively registered).

Indexed as

Home Care ServicesRecovery of FunctionAgedAnxietyFemaleHumansMaleMiddle AgedPatient DischargeStrokeStroke RehabilitationAnxietyRehabilitationStrokeVery early supported discharge

Identifiers

PMID31706292
PMCPMC6878692

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.