Evidence map›Paper›PMID 31705845›Full record

ArticleJournal of insect physiology2020

Suppression of glycogen synthase expression reduces glycogen and lipid storage during mosquito overwintering diapause.

Bryan King, Shijia Li, Chengyin Liu, Sung Joon Kim, Cheolho Sim

Open access · greenAbstract read
In one paragraph

Article in Journal of insect physiology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
1.1field-weighted citation impact, top 26% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 34 citations in OpenAlex.

  1. Lipid Metabolism in Diapause.Advances in experimental medicine and biology · 2026
    Review
  2. Lipid Metabolism in Relation to Carbohydrate Metabolism.Advances in experimental medicine and biology · 2026
    Review
  3. Insect Lipids: Structure, Classification and Function.Advances in experimental medicine and biology · 2026
    Review
  4. Article
  5. Knockdown ofInsects · 2025
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Bryan KingDepartment of Biology, Baylor University, Waco, TX 76798, USA.
Shijia LiDepartment of Biology, Baylor University, Waco, TX 76798, USA.
Chengyin LiuDepartment of Chemistry, Howard University, Washington, D.C. 20059, USA.
Sung Joon KimDepartment of Chemistry, Howard University, Washington, D.C. 20059, USA. Electronic address: sung.kim@howard.edu.
Cheolho SimDepartment of Biology, Baylor University, Waco, TX 76798, USA. Electronic address: cheolho_sim@baylor.edu.
Baylor University · USHoward University · US

Funding

The Role of the Foxo Pathway in the Control of Culex pipiens DiapauseR15AI139861 · NIAID · BAYLOR UNIVERSITY · PI Cheolho Sim · 2018 to 2026
$1.3M
GLYCOPEPTIDE COMPLEXES WITH BACTERIAL CELL WALLS BY REDORR01GM116130 · NIGMS · WASHINGTON UNIVERSITY · PI PATTI, GARY J · 2015 to 2018
$1.2M
NIAID NIH HHS R15 AI139861NIGMS NIH HHS R01 GM116130
6 · The paper itself

Abstract

During diapause in mosquitoes, efficient storage and utilization of energy are crucial for surviving prolonged periods of developmental arrest and for maximizing reproductive success once diapause is terminated and development recommences. In Culex pipiens, glycogen rapidly accumulates during early diapause (7-10 days after adult eclosion) and it is used to maintain energy homeostasis during the first month of diapause. In this study, a gene encoding glycogen synthase, which converts glucose residues into a polymeric chain for storage as glycogen, was characterized. After dsi-RNA directed against glycogen synthase was injected into mosquitoes programmed for diapause (reared under short day lengths), Cx. pipiens were fed 1% d-[

Indexed as

Gene ExpressionLipid MetabolismAnimalsCulexDiapause, InsectFemaleGlycogenGlycogen SynthaseInsect ProteinsLarvaGlycogenGlycogen SynthaseInsect Proteins

Identifiers

PMID31705845
PMCPMC7266145
OpenAlexW2988705462

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.