Evidence map›Paper›PMID 31705625›Full record

ArticleAnnals of clinical and translational neurology2019

Familial deep cavitating state with a glutathione metabolism defect.

John Rendu, Laetitia Van Noolen, Catherine Garrel, Julie Brocard, Isabelle Marty, Christelle Corne, Julien Fauré, Gérard Besson

Registry-linked trialAbstract readCase Reports
PubMed Full text at PMC Publisher
In one paragraph

Article in Annals of clinical and translational neurology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05206292 (Estimating Prevalence of Inherited Disorders of Sulfur Amino Acids Metabolism in Patients With Psychotic Disorders.), which is not on this map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05206292 naunknown statusnot on this mapstarted 2023, after this paper: background citation

Estimating Prevalence of Inherited Disorders of Sulfur Amino Acids Metabolism in Patients With Psychotic Disorders.

TypeinterventionalSponsorUniversity Hospital, GrenobleRan2023 to 2025Enrolled600ConditionsInherited Metabolic Disorder of Nervous System, SchizophreniaArmsSulfitest
3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

John RenduUniv. Grenoble Alpes, Inserm, U1216, CHU Grenoble Alpes, Grenoble Institut Neurosciences, 38000, Grenoble, France.ORCID 0000-0002-0377-0807
Laetitia Van NoolenCHU Grenoble Alpes, 38000, Grenoble, France.
Catherine GarrelCHU Grenoble Alpes, 38000, Grenoble, France.
Julie BrocardUniv. Grenoble Alpes, Inserm, U1216, Grenoble Institut des Neurosciences, 38000, Grenoble, France.
Isabelle MartyUniv. Grenoble Alpes, Inserm, U1216, Grenoble Institut des Neurosciences, 38000, Grenoble, France.
Christelle CorneCHU Grenoble Alpes, 38000, Grenoble, France.
Julien Fauré *Univ. Grenoble Alpes, Inserm, U1216, CHU Grenoble Alpes, Grenoble Institut Neurosciences, 38000, Grenoble, France.
Gérard Besson *Department of Neurology, CHU, Grenoble Alpes, 38000, Grenoble, France.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Adult genetic disorders causing brain lesions have been mostly described as white matter vanishing diseases. We present here the investigations realized in patients referred for psychiatric disorder with magnetic resonance imaging showing atypical basal ganglia lesions. Genetic explorations of this family revealed a new hereditary disease linked to glutathione metabolism.

Indexed as

Basal Ganglia DiseasesBrain Diseases, Metabolic, InbornAdultGlutathioneHumansMagnetic Resonance ImagingMaleMiddle AgedGlutathioneNIT1

Identifiers

PMID31705625
PMCPMC6917305

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.