Evidence map›Paper›PMID 31705471›Full record

ArticleJournal of general internal medicine2020

Roadblocks to PrEP: What Medical Records Reveal About Access to HIV Pre-exposure Prophylaxis.

Avy A Skolnik, Barbara G Bokhour, Allen L Gifford, Brigid M Wilson, Puja Van Epps

Open access · bronzeAbstract read
In one paragraph

Article in Journal of general internal medicine, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 29 papers.

0numbers the graph read from it
0cells of the map it votes in
29citing papers in PubMed
3.6field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

29 citing papers in PubMed, 43 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 1 country.

Avy A SkolnikCenter for Healthcare Organization and Implementation Research (CHOIR), ENRM Veterans Affairs Medical Center Bedford, Bedford, MA, USA. askolnik@umass.edu.ORCID http://orcid.org/0000-0002-5317-1511
Barbara G BokhourCenter for Healthcare Organization and Implementation Research (CHOIR), ENRM Veterans Affairs Medical Center Bedford, Bedford, MA, USA.
Allen L GiffordSection of General Internal Medicine, Department of Medicine, Boston University School of Medicine, Boston, MA, USA.
Brigid M WilsonLouis Stokes Cleveland Department of Veterans Affairs Medical Center (LSCVAMC), Cleveland, OH, USA.
Puja Van EppsLouis Stokes Cleveland Department of Veterans Affairs Medical Center (LSCVAMC), Cleveland, OH, USA.
Boston University · USLouis Stokes Cleveland VA Medical Center · USUniversity of Massachusetts Amherst · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundPre-exposure prophylaxis (PrEP) has been shown to be efficacious in preventing HIV; however, its uptake remains modest. Given that there are fewer cost barriers to receiving PrEP within VHA than via commercial insurance, VHA represents an ideal setting in which to study other barriers that may impact patients seeking PrEP.

objectiveWe sought to understand potential barriers to obtaining PrEP within the Veterans Health Administration (VHA) through examination of documentation in electronic medical records.

designRetrospective structured chart review, including chart abstractions of notes, referrals, and communications; content analysis of charts from a subsample of patients receiving PrEP in VHA.

participantsOne hundred sixty-one patients prescribed PrEP at 90 sites varying in PrEP prescribing rates. APPROACH: We extracted descriptive information and conducted a qualitative analysis of all PrEP-relevant free-text notes including who initiated the PrEP conversation (patient vs. provider), time interval between request and prescription, reasons for denying PrEP, and patient responses to barriers. KEY

resultsPatients initiated 94% of PrEP conversations and 35% of patients experienced delays receiving PrEP ranging from six weeks to 16 months. Over 70% of cases evidenced barriers to access. Barriers included provider knowledge gaps about PrEP, provider knowledge gaps about VHA systems related to PrEP, confusion or disagreement over clinic purview for PrEP, and provider attitudes or stigma associated with patients seeking PrEP.

conclusionsAlthough PrEP is recommended for HIV prevention in high-risk persons, many PrEP-eligible individuals faced barriers to obtaining a prescription. Current practices place substantial responsibility on patients to request and advocate for this service, in contrast to many other preventive services. Understanding the prevalence and content of PrEP knowledge gaps and attitudinal barriers can inform organizational interventions to increase PrEP access and decrease HIV transmission.

Indexed as

Acquired Immunodeficiency SyndromeAnti-HIV AgentsHIV InfectionsPre-Exposure ProphylaxisHumansMedical RecordsRetrospective StudiesAnti-HIV AgentsHIV/AIDSpatient-provider communicationpre-exposure prophylaxispreventionprimary care

Identifiers

PMID31705471
PMCPMC7080884
OpenAlexW2985370859

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.