Evidence map›Paper›PMID 31705360›Full record

ReviewScience China. Life sciences2020

Oxidative stress, nutritional antioxidants and beyond.

Qiuping Guo, Fengna Li, Yehui Duan, Chaoyue Wen, Wenlong Wang, Lingyu Zhang, Ruilin Huang, Yulong Yin

Abstract readReview
PubMed Publisher
In one paragraph

Review in Science China. Life sciences, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 86 papers.

0numbers the graph read from it
0cells of the map it votes in
86citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

86 citing papers in PubMed.

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  20. Current drug discovery technologies · 2025
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26 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Qiuping GuoLaboratory of Animal Nutritional Physiology and Metabolic Process, Institute of Subtropical Agriculture, Chinese Academy of Sciences, Changsha, 410125, China.
Fengna LiLaboratory of Animal Nutritional Physiology and Metabolic Process, Institute of Subtropical Agriculture, Chinese Academy of Sciences, Changsha, 410125, China. lifengna@isa.ac.cn.
Yehui DuanLaboratory of Animal Nutritional Physiology and Metabolic Process, Institute of Subtropical Agriculture, Chinese Academy of Sciences, Changsha, 410125, China.
Chaoyue WenLaboratory of Animal Nutrition and Human Health, School of Biology, Hunan Normal University, Changsha, 410018, China.
Wenlong WangLaboratory of Animal Nutrition and Human Health, School of Biology, Hunan Normal University, Changsha, 410018, China.
Lingyu ZhangLaboratory of Animal Nutritional Physiology and Metabolic Process, Institute of Subtropical Agriculture, Chinese Academy of Sciences, Changsha, 410125, China.
Ruilin HuangLaboratory of Animal Nutritional Physiology and Metabolic Process, Institute of Subtropical Agriculture, Chinese Academy of Sciences, Changsha, 410125, China.
Yulong YinLaboratory of Animal Nutritional Physiology and Metabolic Process, Institute of Subtropical Agriculture, Chinese Academy of Sciences, Changsha, 410125, China. yinyulong@isa.ac.cn.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Free radical-induced oxidative stress contributes to the development of metabolic syndromes (Mets), including overweight, hyperglycemia, insulin resistance and pro-inflammatory state. Most free radicals are generated from the mitochondrial electron transport chain; under physiological conditions, their levels are maintained by efficient antioxidant systems. A variety of transcription factors have been identified and characterized that control gene expression in response to oxidative stress status. Natural antioxidant compounds have been largely studied for their strong antioxidant capacities. This review discusses the recent progress in oxidative stress and mitochondrial dysfunction in Mets and highlights the anti-Mets, anti-oxidative, and anti-inflammatory effect of polyphenols as potential nutritional therapy.

Indexed as

AnimalsAnti-Inflammatory AgentsAntioxidantsBiological ProductsGene Expression RegulationHumansMetabolic SyndromeNutrition DisordersNutrition TherapyOxidative StressPolyphenolsReactive Oxygen SpeciesAnti-Inflammatory AgentsAntioxidantsBiological ProductsPolyphenolsReactive Oxygen Speciesmitochondrial dysfunctionnutritional antioxidantoxidative stresspolyphenolsreactive oxygen speciessignal transduction

Identifiers

PMID31705360

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.