ArticleClinical and experimental nephrology2020
Inflammatory serum markers predicting spontaneous ureteral stone passage.
Article in Clinical and experimental nephrology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers, 3 of them syntheses that pooled it.
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Who cites it
18 citing papers in PubMed, 3 syntheses or guidelines pooled it.
- Predictive value of neutrophil to lymphocyte ratio for the clinical outcome of patients with ureteral stones: a systematic review and meta-analysis.BMC urology · 2026Pooled it
- Neutrophil to lymphocyte ratio in urolithiasis: a systematic review.BMC urology · 2025Pooled it
- Predictive value of inflammatory markers for the spontaneous passage of Ureteral stones: a comprehensive systematic review with meta analysis.Urolithiasis · 2024Pooled it
- The application of new type ureteroscope and traditional linear ureteroscope in ureteric stone patients.BMC urology · 2024Trial
- Role of ureteral wall thickness and computed tomography imaging in predicting spontaneous passage of ureteral stones.Diagnostic and interventional radiology (Ankara, Turkey) · 2026Article
- Article
- Evaluating blood and urinary markers for prediction of spontaneous ureteral stone passage.American journal of clinical and experimental urology · 2025Article
- Association of neutrophil to lymphocyte ratio with all-cause and cardiovascular mortality among individuals with kidney stone disease: result from NHANES, 2007-2018.Frontiers in endocrinology · 2025Article
- Association between the systemic inflammation response index and kidney stones in US adults: a cross-sectional study based on NHANES 2007-2018.Urolithiasis · 2024Article
- Inflammatory cytokines and their potential role in kidney stone disease: a Mendelian randomization study.International urology and nephrology · 2024Article
- Article
- Association between monocyte to high-density lipoprotein cholesterol ratio and kidney stone: insights from NHANES.Frontiers in endocrinology · 2024Article
- Development of a new scoring system predicting medical expulsive therapy success on 4-10 mm distal ureteral stones: medical expulsive therapy stone score (METSS).Urolithiasis · 2023Article
- Association between the systemic immune-inflammation index and kidney stone: A cross-sectional study of NHANES 2007-2018.Frontiers in immunology · 2023Article
- The role of inflammatory serum markers and ureteral wall thickness on spontaneous passage of ureteral stone < 10 mm: A prospective cohort study.Annals of medicine and surgery (2012) · 2022Article
- Does volume matter? Incorporating estimated stone volume in a nomogram to predict ureteral stone passage.Canadian Urological Association journal = Journal de l'Association des urologues du Canada · 2022Article
- Is it possible to predict spontaneous passage of a ureteral stone? An up-to-date comment on the current problem with new concepts concerning the patient and the stone.Central European journal of urology · 2022Article
- Article
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Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
introductionUreteral stones pose a high economic and medical burden among Emergency Department (ED) admissions. Management strategies vary from expectant therapy to surgical interventions. However, predictors of spontaneous ureteral stone passage are still not well understood. We aim to explore the role of neutrophil-to-lymphocyte (NLR) and platelet-to-lymphocyte (PLR) ratios in the spontaneous ureteral stone passage (SSP).
methodsChart review was done for 619 patients who presented to our institution's ED with non-febrile renal colic and received a radiological diagnosis of ureteral stone of less than 10 mm. Demographic, clinical, laboratory, and radiological data were collected. The Linear-by-Linear Association test was used to look at the trend among the NLR and PLR quartiles and other demographic variables. Univariate analysis was run for the collected variables. Then, a hierarchal backward multivariate logistic regression was run for each of NLR and PLR variables. To validate the results, bootstrapping was undertaken for each model.
resultsNLR between 2.87 and 4.87 had odds ratio (OR) 2.96 (95% CI 1.80-5.49) and an NLR > 4.87 had 3.63 (2.04-6.69) the odds of retained ureteral stone. A PLR between 10.42 and 15.25 and a PLR > 15.25 had 3.28 (1.79-6.19) and 3.84 (2.28-7.12) the odds of failed SSP, respectively. Other significant variables in the two models are diabetes, urine leukocyte esterase > 10 white blood cell/μl, moderate-to-severe hydronephrosis, and stone size.
conclusionNLR and PLR are inversely associated with SSP of ureteral stones. In adjunct with other indicators, NLR and PLR are inflammatory markers that could be used in the clinical decision of ureteral stone management.
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