Evidence map›Paper›PMID 31705274›Full record

ArticleEuropean journal of applied physiology2020

Knee extension with blood flow restriction: Impact of cuff pressure on hemodynamics.

Tyler J Singer, Jon Stavres, Steven J Elmer, Matthew A Kilgas, Brandon S Pollock, Sarah G Kearney, John McDaniel

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Article in European journal of applied physiology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed.

  1. Trial
  2. Article
  3. Article
  4. Tourniquet cuff pressure during blood flow restriction exercise.Frontiers in sports and active living · 2025
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  6. Article
  7. Observational
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Tyler J SingerDepartment of Exercise Physiology, Kent State University, Kent, OH, 44242, USA. tsinger4@kent.edu.ORCID http://orcid.org/0000-0002-1301-3957
Jon StavresHeart and Vascular Institute, Penn State University College of Medicine, Hershey, PA, USA.
Steven J ElmerDepartment of Kinesiology and Integrated Physiology, Michigan Technological University, Houghton, MI, USA.
Matthew A KilgasSchool of Health and Human Performance, Northern Michigan University, Marquette, MI, USA.
Brandon S PollockExercise Science Program, Walsh University, North Canton, OH, USA.
Sarah G KearneyDepartment of Exercise Physiology, Kent State University, Kent, OH, 44242, USA.
John McDanielDepartment of Exercise Physiology, Kent State University, Kent, OH, 44242, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionBlood flow restriction (BFR) exercise has emerged as a method of increasing muscle size and strength with low intensity resistance training. While the cuff pressures used during BFR are typically a percentage of resting arterial occlusion pressure (AOP), the impact these cuff pressures have on blood flow during lower body exercise is unknown. PURPOSE: To determine how various cuff pressures impact blood flow and tissue perfusion during exercise.

methodsEleven healthy male participants completed four sets of knee extension (30 reps per set at 30% max torque) with 0%, 60%, 80%, and 100% of arterial occlusion pressure (AOP) was applied to the proximal portion of the thigh. Femoral artery blood flow, tissue oxygenation, and central hemodynamics were continuously recorded before, during, and after exercise. Electromyography (EMG) amplitude was recorded from the vastus lateralis during exercise.

resultsBlood flow increased during exercise compared to rest across all cuff pressures (p < 0.001), however compared to 0%, the absolute blood flow was reduced by 34 ± 17%, 45 ± 22%, and 72 ± 19% for 60, 80, and 100% AOP, respectively. Furthermore, each cuff pressure resulted in similar relative changes in blood flow before, during, and after exercise. During exercise, tissue saturation index (TSI) decreased as cuff pressure increased (p ≤ 0.005) with the exception of 80 to 100% AOP. Deoxyhemoglobin increased (p ≤ 0.001) with cuff pressure.

conclusionOur data indicate that while BFR knee extension elicits an absolute hyperemic response at cuff pressures up to 100% resting AOP, the relative reductions in blood flow are consistent across rest, exercise and recovery.

Indexed as

HemodynamicsRegional Blood FlowAdultCompression BandagesHumansIschemic PreconditioningKneeMaleMuscle ContractionMuscle, SkeletalPressureResistance TrainingArterial occlusionBlood flow restrictionNear inferred spectroscopyResistance exercise

Identifiers

PMID31705274

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.