Evidence map›Paper›PMID 31705252›Full record

Trial reportEuropean radiology2020

Portable ultrasound-guided high-intensity focused ultrasound with functions for safe and rapid ablation: prospective clinical trial for uterine fibroids-short-term and long-term results.

Jae Young Lee, Hyun Hoon Chung, Soo Yeon Kang, Eun-Joo Park, Dong Hyuk Park, Keonho Son, Joon Koo Han

Abstract readClinical Trial
PubMed Publisher
In one paragraph

Trial report in European radiology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed, 3 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

22 citing papers in PubMed, 3 syntheses or guidelines pooled it.

  1. Pooled it
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  6. Focused Ultrasound for Sarcomas: A Narrative Review.Current oncology (Toronto, Ont.) · 2025
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Jae Young LeeDepartment of Radiology and the Institute of Radiation Medicine, Seoul National University Hospital, 101 Daehak-ro, Jongno-gu, Seoul, 03080, Republic of Korea. leejy4u@snu.ac.kr.ORCID http://orcid.org/0000-0001-6946-6042
Hyun Hoon ChungDepartment of Obstetrics & Gynecology, Seoul National University Hospital, 101 Daehak-ro, Jongno-gu, Seoul, 110-744, Republic of Korea.
Soo Yeon KangDepartment of Radiology and the Institute of Radiation Medicine, Seoul National University Hospital, 101 Daehak-ro, Jongno-gu, Seoul, 03080, Republic of Korea.
Eun-Joo ParkDepartment of Radiology and the Institute of Radiation Medicine, Seoul National University Hospital, 101 Daehak-ro, Jongno-gu, Seoul, 03080, Republic of Korea.
Dong Hyuk ParkDepartment of Radiology and the Institute of Radiation Medicine, Seoul National University Hospital, 101 Daehak-ro, Jongno-gu, Seoul, 03080, Republic of Korea.
Keonho SonTherapeutic Ultrasound Division, Alpinion Medical Systems Co., Ltd. Verdi Tower, 72, Digital-ro 26-gil, Guro-gu, Seoul, Republic of Korea.
Joon Koo HanDepartment of Radiology and the Institute of Radiation Medicine, Seoul National University Hospital, 101 Daehak-ro, Jongno-gu, Seoul, 03080, Republic of Korea.

Funding

MOTIE (Ministry of Trade, Industry and Energy)/KEIT (Korean Evaluation Institute of Industrial Technology) 10043474
6 · The paper itself

Abstract

objectivesTo investigate the efficacy and safety of a new portable ultrasound-guided high-intensity focused ultrasound system (USgHIFU) with advanced targeting and beam steering technology for the treatment of uterine fibroids.

methodsFifty-nine uterine fibroids from 36 participants (mean age, 44.9 ± 4.1 years) were included from November 2013 to November 2015. All participants were treated with HIFU, with 3D electronic steering. MR imaging studies were performed before HIFU, immediately after HIFU, and 1 month and 3 (or 5) months after the HIFU treatment. The non-perfused volume ratio (NPVR), fibroid volume shrinkage (FVS), symptom improvement, quantified life quality assessment, and safety were analyzed. A long-term follow-up was conducted in July to December 2017 (mean, 32.2 months).

resultsThe volume of the treated uterine fibroids ranged from 7.5 to 274.4 cm

conclusionThis clinical trial showed that a portable USgHIFU with advanced functions may safely and effectively treat uterine fibroids. KEY POINTS: • A portable compact ultrasound-guided high-intensity focused ultrasound (HIFU) can effectively and safely treat uterine fibroids. • Advanced functions, such as portability, targeted forecasting, electronic beam steering, and interleaved scanning, might be helpful in enhancing the clinical applicability of ultrasound-guided high-intensity focused ultrasound. • In the long-term follow-up of more than 2 years, approximately 80% of those surveyed were satisfied with their HIFU treatment.

Indexed as

Quality of LifeAdultFemaleHigh-Intensity Focused Ultrasound AblationHumansLeiomyomaMagnetic Resonance ImagingMiddle AgedPersonal SatisfactionProspective StudiesTherapy, Computer-AssistedTreatment OutcomeUltrasonography, InterventionalUterine NeoplasmsHigh-intensity focused ultrasound ablationLeiomyoma, uterineTreatment efficacyUltrasonography, interventionalUterine fibroid

Identifiers

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.