Observational studyInternational journal of colorectal disease2019
High risk of septic complications following surgery for Crohn's disease in patients with preoperative anaemia, hypoalbuminemia and high CRP.
Observational study in International journal of colorectal disease, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 32 papers, 2 of them syntheses that pooled it.
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Who cites it
32 citing papers in PubMed, 2 syntheses or guidelines pooled it, 61 citations in OpenAlex.
- Risk Factors and Predictive Biomarkers for Postoperative Complications in Crohn's Disease Surgery: Systematic Review.International journal of molecular sciences · 2026Pooled it
- Nutrition, Nutritional Status, Micronutrients Deficiency, and Disease Course of Inflammatory Bowel Disease.Nutrients · 2023Pooled it
- Article
- Biologic Therapy and Surgical Management in Crohn's Disease: Postoperative Outcomes and Biologic Management Patterns in a Retrospective Cohort Study.Medicina (Kaunas, Lithuania) · 2026Article
- Mucosal fungal dysbiosis is associated with early postoperative endoscopic recurrence after bowel resection for Crohn's disease.International journal of colorectal disease · 2026Article
- Patients at high risk of postoperative complications in Crohn's disease: a meta-analysis and systematic review.Archives of medical science : AMS · 2026Review
- Duodenal Stenting in Complicated Crohn's Disease: Novel Management of Complete Discontinuity of the Small Bowel.ACG case reports journal · 2025Article
- Influencing factors and preventive measures of infectious complications after intestinal resection for Crohn's disease.World journal of gastrointestinal surgery · 2024Article
- Predicting short-term major postoperative complications in intestinal resection for Crohn's disease: A machine learning-based study.World journal of gastrointestinal surgery · 2024Article
- Longitudinal Measurements of Blood Biomarkers in Patients with Crohn's Disease or Ulcerative Colitis Treated with Infliximab: Only the Latest Values in the Induction Period Predict Treatment Failure.Journal of clinical medicine · 2024Article
- Management of acute diverticulitis in Stage 0-IIb: indications and risk factors for failure of conservative treatment in a series of 187 patients.Scientific reports · 2024Article
- Risk and management of post-operative infectious complications in inflammatory bowel disease: A systematic review.World journal of gastrointestinal surgery · 2023Article
- Crohn's Disease as a Possible Risk Factor for Failed Healing in Ileocolic Anastomoses.Journal of clinical medicine · 2023Article
- Factors associated with stoma formation in ileocolic resection for Crohn's disease and the development of a predictive scoring system.Langenbeck's archives of surgery · 2022Article
- Analysis of risk factors for perioperative complications in spine surgery.Scientific reports · 2022Article
- High complication rate in Crohn's disease surgery following percutaneous drainage of intra-abdominal abscess: a multicentre study.International journal of colorectal disease · 2022Observational
- Post-operative morbidity in Crohn's disease: what is the impact of patient-, disease- and surgery-related factors?International journal of colorectal disease · 2022Article
- Retrospective Study of Surgical Outcomes in 60 Patients with Crohn Disease from a Single Center in Poland.Medical science monitor : international medical journal of experimental and clinical research · 2022Article
- C-reactive protein is associated with postoperative outcomes in patients with intestinal Behçet's disease.BMC gastroenterology · 2021Article
- Preoperative assessment of skeletal muscle mass during magnetic resonance enterography in patients with Crohn's disease.Updates in surgery · 2021Article
Corrections and comments
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Authors and funding
5 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
aimBowel resection in Crohn's disease still has a high rate of complications due to risk factors including immune suppression, malnutrition and active inflammation or infection at the time of operating. In this study, we use serological levels and inflammatory markers to predict the potential of complications in patients undergoing resections for complicated Crohn's disease.
methodsAll patients undergoing laparoscopic bowel resection for Crohn's disease from 5th of November 2012 to 11th of October 2017 were included in this retrospective observational study. Patients were divided into 4 groups scoring 0, 1, 2 or 3 depending on their pre-operative haemoglobin concentration (Hb), C-reactive protein (CRP) and albumin (Alb) where 1 point was given for an abnormal value in each as detailed in the definitions. They were then grouped into a low risk group comprised of those scoring 0 and 1, and a high risk group for those scoring 2 and 3 and data was collected to compare outcomes and the incidence of septic complications.
resultsSeventy-nine patients were included. Eleven (13.9%) and 2 (2.5%) patients had 2 or 3 abnormal values of CRP, Alb and Hb and were categorized as high risk. High risk patients had a significantly higher rate of post-operative septic complications (30.7%) compared with low risk patients (10.6%) p value < 0.0001.
conclusionPre-operative CRP, haemoglobin and albumin can serve as predictors of septic complications after surgery for Crohn's disease and can therefore be used to guide pre-operative optimisation and clinical decision-making.
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