Evidence map›Paper›PMID 31705180›Full record

ArticleNeuroradiology2020

Atherosclerotic ICA stenosis coinciding with ICA asymmetry associated with Circle of Willis variations can mimic near-occlusion.

Elias Johansson, Richard I Aviv, Allan J Fox

Open access · hybridAbstract read
In one paragraph

Article in Neuroradiology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed, 1 pooled it
2.6field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 1 synthesis or guideline pooled it, 26 citations in OpenAlex.

  1. Pooled it
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  4. Review
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  7. Article
  8. Article
  9. Review
  10. Symmetry and asymmetry in atherosclerosis.International journal of occupational medicine and environmental health · 2023
    Review
  11. Article
  12. Article
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  15. Article
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  18. Diagnosing Carotid Near-Occlusion with Phase-Contrast MRI.AJNR. American journal of neuroradiology · 2021
    Article
  19. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 2 countries.

Elias JohanssonDepartment Clinical Science, and Wallenberg Center for Molecular Medicine (WCMM), Umeå University, Umeå, Sweden. elias.johansson@umu.se.ORCID https://orcid.org/0000-0001-5317-4563
Richard I AvivDepartment of Medical Imaging, Sunnybrook Health Science Center, University of Toronto, Toronto, Canada.
Allan J FoxDepartment of Medical Imaging, Sunnybrook Health Science Center, University of Toronto, Toronto, Canada.ORCID https://orcid.org/0000-0001-5465-5801
Sunnybrook Health Science Centre · CAUmeå University · SE

Funding

Knut och Alice Wallenbergs Stiftelse -Region Västerbotten -Resarch Fund of Neurological Research at the University Hosptial of Northern Sweden -Svenska Läkaresällskapet -The Northern Swedish Stroke Foundation -
6 · The paper itself

Abstract

Differentiating carotid near-occlusion (tight atherosclerotic stenosis causing distal artery size reduction) from conventional stenosis is the first step when grading carotid stenoses with NASCET method. The internal carotid artery (ICA) can be asymmetrically associated with Circle of Willis variations. When such ICA asymmetry coincides with stenosis, it may mimic near-occlusion. We studied ICA anatomical variant prevalence in 4042 consecutive CTA exams from all indications, 53 excluded due to carotid occlusion, 814 with any ≥ 50% steno-occlusive disease intra- or extracranially, 3228 without. Of the 3989 included cases, 568 (14%) had ICA asymmetry, of which 335 (59%) were from associated with Circle of Willis variations. Of 3228 patients without ≥ 50% stenosis or other steno-occlusive disease intra- and extracranially; 257 (8.0%) demonstrated ICA asymmetry associated with Circle of Willis variations, equally common among sexes and age unrelated and most frequently attributed to an ipsilateral A1 hypoplasia/aplasia, less often attributed to large contralateral posterior communicating artery. As ICA asymmetry associated with Circle of Willis variations are common, caution should be exercised diagnosing near-occlusion on asymmetry alone.

Indexed as

AtherosclerosisCarotid StenosisCircle of WillisDiagnosis, DifferentialHumansRetrospective StudiesCarotid arteryCarotid stenosisComputed tomography angiographyNear-occlusion

Identifiers

PMID31705180
PMCPMC6940316
OpenAlexW2988665926

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.