ArticleScientific reports2019
Species-wide Metabolic Interaction Network for Understanding Natural Lignocellulose Digestion in Termite Gut Microbiota.
Article in Scientific reports, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.
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Who cites it
18 citing papers in PubMed.
- Disentangling Gut Bacterial Community Patterns inInsects · 2025Article
- Genome-Scale Community Model-Guided Development of Bacterial Coculture for Lignocellulose Bioconversion.Biotechnology and bioengineering · 2025Article
- Advanced Membrane Simulations in Probiotics and Gut Microbiome Interaction Research: The Current Trends and Insights.Current pharmaceutical design · 2025Review
- Enzymatic Regulation of the Gut Microbiota: Mechanisms and Implications for Host Health.Biomolecules · 2024Review
- Top-down and bottom-up microbiome engineering approaches to enable biomanufacturing from waste biomass.Journal of industrial microbiology & biotechnology · 2024Review
- Isolation and characterization of intestinal bacteria associated with cellulose degradation in grasshoppers (Orthoptera).Journal of insect science (Online) · 2023Article
- Analysis of Intestinal Microbial Diversity of Four Species of Grasshoppers and Determination of Cellulose Digestibility.Insects · 2022Article
- Two Apriona Species Sharing a Host Niche Have Different Gut Microbiome Diversity.Microbial ecology · 2022Article
- Of Cockroaches and Symbionts: Recent Advances in the Characterization of the Relationship betweenLife (Basel, Switzerland) · 2022Review
- Lessons From Insect Fungiculture: From Microbial Ecology to Plastics Degradation.Frontiers in microbiology · 2022Article
- Gut Microbiota ofFrontiers in microbiology · 2022Article
- Article
- Unlocking the potential of insect and ruminant host symbionts for recycling of lignocellulosic carbon with a biorefinery approach: a review.Microbial cell factories · 2021Review
- Metagenomics for taxonomy profiling: tools and approaches.Bioengineered · 2020Article
- How gut microbiome interactions affect nutritional traits ofThe Journal of experimental biology · 2020Article
- Ignoring social distancing: advances in understanding multi-species bacterial interactions.Faculty reviews · 2020Review
- Article
- Targeted Metagenomics of Retting in Flax: The Beginning of the Quest to Harness the Secret Powers of the Microbiota.Frontiers in genetics · 2020Review
Corrections and comments
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4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The structural complexity of lignocellulosic biomass hinders the extraction of cellulose, and it has remained a challenge for decades in the biofuel production process. However, wood-feeding organisms like termite have developed an efficient natural lignocellulolytic system with the help of specialized gut microbial symbionts. Despite having an enormous amount of high-throughput metagenomic data, specific contributions of each individual microbe to achieve this lignocellulolytic functionality remains unclear. The metabolic cross-communication and interdependence that drives the community structure inside the gut microbiota are yet to be explored. We have contrived a species-wide metabolic interaction network of the termite gut-microbiome to have a system-level understanding of metabolic communication. Metagenomic data of Nasutitermes corniger have been analyzed to identify microbial communities in different gut segments. A comprehensive metabolic cross-feeding network of 205 microbes and 265 metabolites was developed using published experimental data. Reconstruction of inter-species influence network elucidated the role of 37 influential microbes to maintain a stable and functional microbiota. Furthermore, in order to understand the natural lignocellulose digestion inside N. corniger gut, the metabolic functionality of each influencer was assessed, which further elucidated 15 crucial hemicellulolytic microbes and their corresponding enzyme machinery.
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