Evidence map›Paper›PMID 31704799›Full record

ArticleBMJ case reports2019

Meningitis due to non-steroidal anti-inflammatory drugs: an often-overlooked complication of a widely used medication.

Florian Desgranges, Nathalie Tebib, Olivier Lamy, Antonios Kritikos

Open access · hybridAbstract readCase Reports
In one paragraph

Article in BMJ case reports, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
1.0field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 14 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Florian DesgrangesInfectious Diseases, Centre Hospitalier Universitaire Vaudois, Lausanne, Switzerland florian.desgranges@chuv.ch.
Nathalie TebibInternal Medicine, Centre Hospitalier Universitaire Vaudois, Lausanne, Switzerland.
Olivier LamyInternal Medicine, Centre Hospitalier Universitaire Vaudois, Lausanne, Switzerland.
Antonios KritikosInfectious Diseases, Centre Hospitalier Universitaire Vaudois, Lausanne, Switzerland.
University Hospital of Lausanne · CH

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

A 40-year-old man developed aseptic meningitis after ibuprofen consumption for tension-type headaches. After a thorough diagnostic workup and lack of improvement on empirical therapy for common aetiologies of meningitis (bacterial and viral infections), we suspected non-steroidal anti-inflammatory drug (NSAID) induced meningitis due to the temporal relationship between drug administration and symptom onset. Two days after NSAID suppression, the evolution was progressively favourable with complete resolution of fever and symptoms. On follow-up, symptoms did not recur and there was no neurological sequela. This article summarises the clinical picture and the complementary exams that led to the difficult-to-make diagnosis of NSAID-induced acute meningitis, in parallel with a brief review of the literature.

Indexed as

AdultAnti-Inflammatory Agents, Non-SteroidalDiagnosis, DifferentialHumansIbuprofenMaleMeningitis, AsepticAnti-Inflammatory Agents, Non-SteroidalIbuprofencontraindications and precautionsheadache (including migraines)meningitis

Identifiers

PMID31704799
PMCPMC6855853
OpenAlexW2988760732

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.