Evidence map›Paper›PMID 31704768›Full record

ArticleProceedings of the National Academy of Sciences of the United States of America2019

Early sarcomere and metabolic defects in a zebrafish

Michelle M Collins, Gustav Ahlberg, Camilla Vestergaard Hansen, Stefan Guenther, Rubén Marín-Juez, Anna M Sokol, Hadil El-Sammak, Janett Piesker, Ylva Hellsten, Morten S Olesen and 2 more

Open access · bronzeAbstract read
In one paragraph

Article in Proceedings of the National Academy of Sciences of the United States of America, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 33 papers.

0numbers the graph read from it
0cells of the map it votes in
33citing papers in PubMed
2.0field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

33 citing papers in PubMed, 45 citations in OpenAlex.

  1. Article
  2. Protein turnover downstream of the Nipbl/CRL4 axis contributes to abnormal development in zebrafish embryos.Developmental dynamics : an official publication of the American Association of Anatomists · 2026
    Article
  3. Review
  4. Single-Nucleotide Polymorphisms,International journal of molecular sciences · 2025
    Review
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Zebrafish Congenital Heart Disease Models: Opportunities and Challenges.International journal of molecular sciences · 2024
    Review
  13. Loss of Cardiac Splicing RegulatorJACC. Basic to translational science · 2024
    Article
  14. Review
  15. Advances in basic and translational research in atrial fibrillation.Philosophical transactions of the Royal Society of London. Series B, Biological sciences · 2023
    Review
  16. Review
  17. Review
  18. Article
  19. Article
  20. Altered Expression ofInternational journal of molecular sciences · 2022
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 2 institutions in 2 countries.

Michelle M CollinsDepartment of Developmental Genetics, Max Planck Institute for Heart and Lung Research, D-61231 Bad Nauheim, Germany; michelle.collins@mpi-bn.mpg.de didier.stainier@mpi-bn.mpg.de plundegaard@sund.ku.dk.ORCID 0000-0002-8439-5278
Gustav AhlbergLaboratory for Molecular Cardiology, Department of Cardiology, Vascular, Pulmonary and Infectious Diseases, University Hospital of Copenhagen, 2100 Copenhagen, Denmark.
Camilla Vestergaard HansenDepartment of Nutrition, Exercise and Sport, University of Copenhagen, 2200 Copenhagen, Denmark.
Stefan GuentherBioinformatics and Deep Sequencing Platform, Max Planck Institute for Heart and Lung Research, D-61231 Bad Nauheim, Germany.
Rubén Marín-JuezDepartment of Developmental Genetics, Max Planck Institute for Heart and Lung Research, D-61231 Bad Nauheim, Germany.
Anna M SokolDepartment of Developmental Genetics, Max Planck Institute for Heart and Lung Research, D-61231 Bad Nauheim, Germany.
Hadil El-SammakDepartment of Developmental Genetics, Max Planck Institute for Heart and Lung Research, D-61231 Bad Nauheim, Germany.
Janett PieskerMicroscopy Service Group, Max Planck Institute for Heart and Lung Research, D-61231 Bad Nauheim, Germany.
Ylva HellstenDepartment of Nutrition, Exercise and Sport, University of Copenhagen, 2200 Copenhagen, Denmark.
Morten S OlesenLaboratory for Molecular Cardiology, Department of Cardiology, Vascular, Pulmonary and Infectious Diseases, University Hospital of Copenhagen, 2100 Copenhagen, Denmark.
Didier Y R StainierDepartment of Developmental Genetics, Max Planck Institute for Heart and Lung Research, D-61231 Bad Nauheim, Germany; michelle.collins@mpi-bn.mpg.de didier.stainier@mpi-bn.mpg.de plundegaard@sund.ku.dk.
Pia R LundegaardLaboratory for Molecular Cardiology, Department of Cardiology, Vascular, Pulmonary and Infectious Diseases, University Hospital of Copenhagen, 2100 Copenhagen, Denmark; michelle.collins@mpi-bn.mpg.de didier.stainier@mpi-bn.mpg.de plundegaard@sund.ku.dk.ORCID 0000-0002-8284-1844
Max Planck Institute for Heart and Lung Research · DEUniversity of Copenhagen · DK

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Atrial fibrillation (AF) is the most common type of cardiac arrhythmia. The major AF susceptibility locus 4q25 establishes long-range interactions with the promoter of

Indexed as

AcetylcysteineAnimalsAnimals, Genetically ModifiedAntioxidantsArrhythmias, CardiacCardiac Conduction System DiseaseCardiomyopathiesDisease Models, AnimalElectrocardiographyGene Expression RegulationHomeodomain ProteinsLarvaMitochondria, HeartSarcomeresStress, PhysiologicalTranscription FactorsAcetylcysteineAntioxidantsHomeodomain Proteinspitx2c protein, zebrafishPitx2 protein, zebrafishTranscription FactorsZebrafish Proteinscardiac developmentcardiac metabolismcardiomyopathytranscriptional profiling

Identifiers

PMID31704768
PMCPMC6883774
OpenAlexW2984293203

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.