Evidence map›Paper›PMID 31704721›Full record

ArticlePlant physiology2020

A Theophylline-Responsive Riboswitch Regulates Expression of Nuclear-Encoded Genes.

Nana Shanidze, Felina Lenkeit, Jörg S Hartig, Dietmar Funck

Open access · hybridAbstract read
In one paragraph

Article in Plant physiology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
1.1field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 28 citations in OpenAlex.

  1. Review
  2. Tunable gene expression in zebrafish using RiboSCALE.bioRxiv : the preprint server for biology · 2026
    Article
  3. Review
  4. Review
  5. Review
  6. Article
  7. Review
  8. Review
  9. Aptamers' Potential to Fill Therapeutic and Diagnostic Gaps.Pharmaceuticals (Basel, Switzerland) · 2024
    Article
  10. Review
  11. Review
  12. Review
  13. Article
  14. Cell-free riboswitches.RSC chemical biology · 2021
    Review
  15. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Nana ShanidzeDepartment of Biology, University of Konstanz, 78464 Konstanz, Germany.ORCID 0000-0001-9647-2130
Felina LenkeitDepartment of Biology, University of Konstanz, 78464 Konstanz, Germany.
Jörg S HartigDepartment of Chemistry, University of Konstanz, 78464 Konstanz, Germany.
Dietmar FunckDepartment of Biology, University of Konstanz, 78464 Konstanz, Germany dietmar.funck@uni-konstanz.de.ORCID 0000-0002-9855-0419
University of Konstanz · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Riboswitches are small cis-regulatory RNA elements that regulate gene expression by conformational changes in response to ligand binding. Synthetic riboswitches have been engineered as versatile and innovative tools for gene regulation by external application of their ligand in prokaryotes and eukaryotes. In plants, synthetic riboswitches were used to regulate gene expression in plastids, but the application of synthetic riboswitches for the regulation of nuclear-encoded genes in planta remains to be explored. Here, we characterize the properties of a theophylline-responsive synthetic aptazyme for control of nuclear-encoded transgenes in Arabidopsis (

Indexed as

3' Untranslated RegionsArabidopsis ProteinsChlorophyll Binding ProteinsGene Expression Regulation, BacterialPromoter Regions, GeneticRiboswitchRNA StabilityTheophylline3' Untranslated RegionsArabidopsis ProteinsChlorophyll Binding ProteinsOHP1 protein, ArabidopsisRiboswitchTheophylline

Identifiers

PMID31704721
PMCPMC6945857
OpenAlexW2986427315

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.