ArticleDevelopmental cognitive neuroscience2019
Simultaneous EEG and fMRI reveals stronger sensitivity to orthographic strings in the left occipito-temporal cortex of typical versus poor beginning readers.
Article in Developmental cognitive neuroscience, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers, 3 of them syntheses that pooled it.
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Who cites it
24 citing papers in PubMed, 3 syntheses or guidelines pooled it.
- Culture Shapes the Neural Functional Alteration and Its Development in Children With Dyslexia: A Cross-Linguistic Meta-Analysis.Developmental science · 2026Pooled it
- Event-related potentials in the "Triangle" framework of reading and developmental dyslexia: a systematic review.Annals of dyslexia · 2026Pooled it
- Typical and Atypical Development of Visual Expertise for Print as Indexed by the Visual Word N1 (N170w): A Systematic Review.Frontiers in neuroscience · 2022Pooled it
- Dynamic behavioral and neural correlates of letter-speech sound learning in typical and dyslexic readers.NPJ science of learning · 2026Article
- Text Sequence Stimulation for High-Speed and Comfortable SSVEP-BCI.Cyborg and bionic systems (Washington, D.C.) · 2026Article
- Toward a Mechanistic Understanding of Reading Difficulties: Deviant Audiovisual Learning Dynamics and Network Connectivity in Children with Poor Reading Skills.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2025Article
- Beyond Letters: Optimal Transport as a Model for Sub-Letter Orthographic Processing.Neurobiology of language (Cambridge, Mass.) · 2025Article
- Differential weighting of information during aloud and silent reading: Evidence from representational similarity analysis of fMRI data.Imaging neuroscience (Cambridge, Mass.) · 2025Article
- Unraveling individual differences in learning potential: A dynamic framework for the case of reading development.Developmental cognitive neuroscience · 2024Review
- Can prediction error explain predictability effects on the N1 during picture-word verification?Imaging neuroscience (Cambridge, Mass.) · 2024Article
- Lexical and sublexical cortical tuning for print revealed by Steady-State Visual Evoked Potentials (SSVEPs) in early readers.Developmental science · 2023Article
- Longitudinal changes in brain activation underlying reading fluency.Human brain mapping · 2023Article
- Brain Source Correlates of Speech Perception and Reading Processes in Children With and Without Reading Difficulties.Frontiers in neuroscience · 2022Article
- Anatomy and physiology of word-selective visual cortex: from visual features to lexical processing.Brain structure & function · 2021Review
- Orthographic Processing of Developmental Dyslexic Children in China: Evidence from an Event-Related Potential Study.Current medical science · 2021Article
- Distinct neural sources underlying visual word form processing as revealed by steady state visual evoked potentials (SSVEP).Scientific reports · 2021Article
- Neural patterns of word processing differ in children with dyslexia and isolated spelling deficit.Brain structure & function · 2021Article
- Article
- ERP Correlates of Altered Orthographic-Phonological Processing in Dyslexia.Frontiers in psychology · 2021Article
- Developmental Trajectories of Letter and Speech Sound Integration During Reading Acquisition.Frontiers in psychology · 2021Article
Corrections and comments
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Authors and funding
8 authors.
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No grant is acknowledged in the PubMed record.
Abstract
The level of reading skills in children and adults is reflected in the strength of preferential neural activation to print. Such preferential activation appears in the N1 event-related potential (ERP) over the occipitotemporal scalp after around 150-250 ms and the corresponding blood oxygen level dependent (BOLD) signal in the ventral occipitotemporal (vOT) cortex. Here, orthography-sensitive (print vs. false font) processing was examined using simultaneous EEG-fMRI in 38 first grade children with poor and typical reading skills, and at varying familial risk for developmental dyslexia. Coarse orthographic sensitivity was observed as an increased activation to print in the N1 ERP and in the BOLD signal of individually varying vOT regions in 57% of beginning readers. Finer differentiation in processing orthographic strings (words vs. nonwords) further occurred in specific vOT clusters. Neither method alone showed robust differences in orthography-sensitive processing between typical and poor reading children. Importantly, using single-trial N1 ERP-informed fMRI analysis, we found differential modulation of the orthography-sensitive BOLD response in the left vOT for typical readers only. This result, thus, confirms subtle functional alterations in a brain structure known to be critical for fluent reading at the very beginning of reading instruction.
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