Evidence map›Paper›PMID 31703932›Full record

ReviewSeminars in oncology

HIV and cancer in the Veterans Health Administration System.

Keith Sigel, Lesley Park, Amy Justice

Open access · greenAbstract readReview
In one paragraph

Review in Seminars in oncology. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed, 1 pooled it
1.1field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 1 synthesis or guideline pooled it, 15 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Article
  5. Article
  6. Cancer Microbiology.Journal of the National Cancer Institute · 2022
    Article
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 3 institutions in 1 country.

Keith SigelIcahn School of Medicine at Mount Sinai, NY, NY. Electronic address: keith.sigel@mssm.edu.
Lesley ParkStanford University School of Medicine, Palo Alto, CA.
Amy JusticeVA Connecticut Healthcare System, West Haven, CT; Yale University School of Medicine.
Icahn School of Medicine at Mount Sinai · USPalo Alto University · USVA Connecticut Healthcare System · US

Funding

Optimizing Lung Cancer Treatment in HIV Infected PersonsR01CA210806 · NCI · ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI · PI SIGEL, KEITH MAGNUS · 2017 to 2020
$2.3M
The Cost-Effectiveness of Lung Cancer Screening in HIV InfectionK07CA180782 · NCI · ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI · PI SIGEL, KEITH MAGNUS · 2014 to 2018
$646k
NCI NIH HHS K07 CA180782NCI NIH HHS R01 CA210806
6 · The paper itself

Abstract

Cancer is a leading cause of death for people with HIV (PWH). The Veterans Healthcare System (VA) is the largest single institutional provider of HIV care in the United States. Cancer among Veterans with HIV is major issue and clinical research has expanded significantly during the antiretroviral therapy (ART) era providing numerous insights regarding cancer incidence, risk factors, prevention, treatment and outcomes for this unique group of patients. This work has been greatly facilitated by the availability of national VA data sources. Notably, patterns of cancer incidence have changed for Veterans with HIV during the ART era; non-AIDS defining malignancies now are the most common tumors. Despite better HIV control in the ART era, immunosuppression measured by low CD4 counts and HIV viremia have been associated with increased cancer risk. Cancer outcomes for Veterans with HIV may now be similar to uninfected Veterans, but information on outcomes and cancer treatment patterns remains limited, requiring further study to help inform prevention and treatment strategies.

Indexed as

VeteransFemaleHIV InfectionsHumansIncidenceMaleNeoplasmsResearchRisk AssessmentRisk FactorsUnited StatesVeterans HealthAnti-retroviral eraCancerHIVNon-AIDS defining cancersVeterans Affairs Health System

Identifiers

PMID31703932
PMCPMC7071926
OpenAlexW2981369081

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.