Observational studyBMC cancer2019
A single exercise session improves side-effects of chemotherapy in women with breast cancer: an observational study.
Observational study in BMC cancer, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT02473003 (Physical Training and Cancer- Effects and Understanding of Mechanisms for Prevent and Minimizing Cancer Related Fatigue, Improve Quality of Life and Disease Outcome), which is not on this map. Cited by 15 papers, 3 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Physical Training and Cancer- Effects and Understanding of Mechanisms for Prevent and Minimizing Cancer Related Fatigue, Improve Quality of Life and Disease Outcome
Who cites it
15 citing papers in PubMed, 3 syntheses or guidelines pooled it.
- Impact of resistance training on fatigue among breast cancer patients undergoing chemotherapy: a systematic review and meta-analysis.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2024Pooled it
- Effect of exercise on fatigue and depression in breastcancer women undergoing chemotherapy: a systematic review and meta-analysis.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2024Pooled it
- Different Methods of Physical Training Applied to Women Breast Cancer Survivors: A Systematic Review.Frontiers in physiology · 2021Pooled it
- Trial
- Analysis of human neutrophil phenotypes as biomarker to monitor exercise-induced immune changes.Journal of leukocyte biology · 2021Trial
- Development and usability testing of a health recommender system for symptom management in women with breast cancer who were receiving or had recently received chemotherapy.Asia-Pacific journal of oncology nursing · 2026Article
- Feasibility of an exercise intervention for chemotherapy-related fatigue in patients with gynecologic cancer: a randomized controlled trial with multidimensional assessment.BMC sports science, medicine & rehabilitation · 2026Article
- "It's adjusting the mindset": physical activity participation during chemotherapy.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2026Article
- A Multi-Disciplinary Approach to the Management of Chemotherapy-Induced Nausea and Vomiting in Breast Cancer.Therapeutics and clinical risk management · 2026Review
- Multisymptom Burden in Cancer Survivors: Benefits of Physical Activity.Exercise, sport & movement · 2024Article
- Osteoporosis Associated with Breast Cancer Treatments Based on Types of Hormonal Therapy: A Cross-Sectional Study Using Korean National Sample Data.Medicina (Kaunas, Lithuania) · 2023Article
- Exercise medicine for cancer cachexia: targeted exercise to counteract mechanisms and treatment side effects.Journal of cancer research and clinical oncology · 2022Review
- Article
- Effect of the Rehabilitation Program, ReStOre, on Serum Biomarkers in a Randomized Control Trial of Esophagogastric Cancer Survivors.Frontiers in oncology · 2021Article
- Exercise shapes redox signaling in cancer.Redox biology · 2020Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors.
Funding
Abstract
backgroundTo measure changes in four common chemotherapy related side-effects (low energy, stress, nausea and pain) immediately after a single exercise session within the first week after treatment.
methodsThirty-eight patients with chemotherapy-treated breast cancer, participating in a multi-centre randomised controlled study, the Physical Training and Cancer study (Phys-Can) were included in this sub-study. The Phys-Can intervention included endurance and resistance training. Before and after a single training session (endurance or resistance) within the first week of chemotherapy, energy and stress were measured with the Stress-Energy Questionnaire during Leisure Time, and nausea and pain were assessed using a Visual Analog Scale 0-10. Paired t-tests were performed to analyse the changes, and linear regression was used to analyse associations with potential predictors.
resultsThirty-eight participants performed 26 endurance training sessions and 31 resistance training sessions in the first week after chemotherapy. Energy and nausea improved significantly after endurance training, and energy, stress and nausea improved significantly after resistance training. Energy increased (p = 0.03 and 0.001) and nausea decreased (p = 0.006 and 0.034) immediately after a single session of endurance or resistance training, and stress decreased (p = 0.014) after resistance exercise.
conclusionsBoth endurance and resistance training were followed by an immediate improvement of common chemotherapy-related side-effects in patients with breast cancer. Patients should be encouraged to exercise even if they suffer from fatigue or nausea during chemotherapy.
trial registrationNCT02473003, June 16, 2015.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.