Evidence map›Paper›PMID 31703327›Full record

ReviewViruses2019

Mechanisms Mediating Nuclear Trafficking Involved in Viral Propagation by DNA Viruses.

Guohui Li, Xinyu Qi, Zhaoyang Hu, Qi Tang

Open access · goldAbstract readReview
In one paragraph

Review in Viruses, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
1.1field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 12 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Guohui LiInstitute of Life Sciences, Jiangsu University, Zhenjiang 212013, Jiangsu, China.ORCID 0000-0002-4214-0533
Xinyu QiInstitute of Life Sciences, Jiangsu University, Zhenjiang 212013, Jiangsu, China.
Zhaoyang HuInstitute of Life Sciences, Jiangsu University, Zhenjiang 212013, Jiangsu, China.
Qi TangInstitute of Life Sciences, Jiangsu University, Zhenjiang 212013, Jiangsu, China.
Jiangsu University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Typical viral propagation involves sequential viral entry, uncoating, replication, gene transcription and protein synthesis, and virion assembly and release. Some viral proteins must be transported into host nucleus to facilitate viral propagation, which is essential for the production of mature virions. During the transport process, nuclear localization signals (NLSs) play an important role in guiding target proteins into nucleus through the nuclear pore. To date, some classical nuclear localization signals (cNLSs) and non-classical NLSs (ncNLSs) have been identified in a number of viral proteins. These proteins are involved in viral replication, expression regulation of viral genes and virion assembly. Moreover, other proteins are transported into nucleus with unknown mechanisms. This review highlights our current knowledge about the nuclear trafficking of cellular proteins associated with viral propagation.

Indexed as

Nuclear Localization SignalsVirus ReplicationCapsidCell NucleusDNA VirusesGenome, ViralNuclear PoreProtein TransportViral ProteinsVirionVirus AssemblyVirus InternalizationNuclear Localization SignalsViral ProteinscNLSsexpression regulationncNLSsNLSsviral propagationviral replicationvirion assembly

Identifiers

PMID31703327
PMCPMC6893576
OpenAlexW2987239500

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.