Evidence map›Paper›PMID 31703295›Full record

ArticleAntioxidants (Basel, Switzerland)2019

Combination of PDT and NOPDT with a Tailored BODIPY Derivative.

Loretta Lazzarato, Elena Gazzano, Marco Blangetti, Aurore Fraix, Federica Sodano, Giulia Maria Picone, Roberta Fruttero, Alberto Gasco, Chiara Riganti, Salvatore Sortino

Open access · goldAbstract read
In one paragraph

Article in Antioxidants (Basel, Switzerland), 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
1.0field-weighted citation impact, top 26% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 22 citations in OpenAlex.

  1. Article
  2. Article
  3. Photochemical Properties and Stability of BODIPY Dyes.International journal of molecular sciences · 2021
    Article
  4. Overcoming drug resistance in glioblastoma: new options in sight?Cancer drug resistance (Alhambra, Calif.) · 2021
    Article
  5. Article
  6. Free Radical Research in Cancer.Antioxidants (Basel, Switzerland) · 2020
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 2 institutions in 1 country.

Loretta LazzaratoDepartment of Drug Science and Technology, University of Torino, 10125 Torino, Italy.ORCID 0000-0001-7100-8593
Elena GazzanoDepartment of Oncology, University of Torino, 10126 Torino, Italy.ORCID 0000-0003-0939-0562
Marco BlangettiDepartment of Chemistry, University of Torino, 10125 Torino, Italy.ORCID 0000-0001-6553-8846
Aurore FraixDepartment of Drug Sciences, University of Catania, 95125 Catania, Italy.ORCID 0000-0002-8328-3290
Federica SodanoDepartment of Drug Science and Technology, University of Torino, 10125 Torino, Italy.ORCID 0000-0003-2013-4893
Giulia Maria PiconeDepartment of Oncology, University of Torino, 10126 Torino, Italy.
Roberta FrutteroDepartment of Drug Science and Technology, University of Torino, 10125 Torino, Italy.
Alberto GascoDepartment of Drug Science and Technology, University of Torino, 10125 Torino, Italy.
Chiara RigantiDepartment of Oncology, University of Torino, 10126 Torino, Italy.ORCID 0000-0001-9787-4836
Salvatore SortinoDepartment of Drug Sciences, University of Catania, 95125 Catania, Italy.
University of Turin · ITUniversity of Catania · IT

Funding

Associazione Italiana per la Ricerca sul Cancro IG-19859European Cooperation in Science and Technology CA17104Ministero dell'Istruzione, dell'Università e della Ricerca LAZL_RILO_18_01
6 · The paper itself

Abstract

The engineering of photosensitizers (PS) for photodynamic therapy (PDT) with nitric oxide (NO) photodonors (NOPD) is broadening the horizons for new and yet to be fully explored unconventional anticancer treatment modalities that are entirely controlled by light stimuli. In this work, we report a tailored boron-dipyrromethene (BODIPY) derivative that acts as a PS and a NOPD simultaneously upon single photon excitation with highly biocompatible green light. The photogeneration of the two key species for PDT and NOPDT, singlet oxygen (

Indexed as

combination therapylightnitric oxidephotodynamic therapysinglet oxygen

Identifiers

PMID31703295
PMCPMC6912809
OpenAlexW2987774111

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.