Evidence map›Paper›PMID 31702971›Full record

ReviewAmerican journal of physiology. Heart and circulatory physiology2019

Adaptive immunity-driven inflammation and cardiovascular disease.

Daria V Ilatovskaya, Ganesh V Halade, Kristine Y DeLeon-Pennell

Open access · bronzeAbstract readReview
In one paragraph

Review in American journal of physiology. Heart and circulatory physiology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.

0numbers the graph read from it
0cells of the map it votes in
23citing papers in PubMed
1.6field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

23 citing papers in PubMed, 33 citations in OpenAlex.

  1. Article
  2. Cellular and molecular signals of cardiac wound healing after myocardial infarction.American journal of physiology. Heart and circulatory physiology · 2026
    Review
  3. Article
  4. Article
  5. The Emerging Role of Senolysis in Atherosclerosis.Medicina (Kaunas, Lithuania) · 2025
    Review
  6. Article
  7. Article
  8. Article
  9. Article
  10. Review
  11. Review
  12. Article
  13. Review
  14. Review
  15. Review
  16. Review
  17. Mesenchymal stem cell-derived extracellular vesicles in the failing heart: past, present, and future.American journal of physiology. Heart and circulatory physiology · 2021
    Review
  18. Review
  19. Single-Cell Analysis Revealed the Role of CD8Frontiers in immunology · 2021
    Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 1 country.

Daria V IlatovskayaDivision of Nephrology, Department of Medicine, Medical University of South Carolina, Charleston, South Carolina.
Ganesh V HaladeDivision of Cardiovascular Disease, Department of Medicine, The University of Alabama at Birmingham, Birmingham, Alabama.
Kristine Y DeLeon-PennellDepartment of Medicine, Division of Cardiology, Medical University of South Carolina, Charleston, South Carolina.ORCID 0000-0002-9647-6112
Medical University of South Carolina · USUniversity of Alabama at Birmingham · US

Funding

The Impact of Stress and Craving on Return to Postpartum Cannabis UseU54DA016511 · NIDA · MEDICAL UNIVERSITY OF SOUTH CAROLINA · PI AIMEE L MCRAE-CLARK · 2018 to 2026
$15.9M
Resolution of Inflammation in Heart Failure Post-Myocardial InfarctionR01HL132989 · NHLBI · UNIVERSITY OF SOUTH FLORIDA · PI HALADE, GANESH V · 2016 to 2020
$1.8M
Lipoxygenase Signaling in Heart Failure PathologyR01HL144788 · NHLBI · UNIVERSITY OF SOUTH FLORIDA · PI HALADE, GANESH V · 2019 to 2022
$1.5M
The involvement of ATP-dependent inhibition of ENaC in ARPKD cystogenesisR00DK105160 · NIDDK · MEDICAL UNIVERSITY OF SOUTH CAROLINA · PI ILATOVSKAYA, DARIA · 2018 to 2020
$747k
The involvement of ATP-dependent inhibition of ENaC in ARPKD cystogenesisK99DK105160 · NIDDK · MEDICAL COLLEGE OF WISCONSIN · PI ILATOVSKAYA, DARIA · 2015 to 2016
$180k
BLRD VA IK2 BX003922NHLBI NIH HHS R01 HL132989NHLBI NIH HHS R01 HL144788NIDA NIH HHS U54 DA016511NIDDK NIH HHS K99 DK105160NIDDK NIH HHS R00 DK105160
6 · The paper itself

Abstract

The adaptive immune response has recently emerged as an important factor in a wide variety of cardiovascular disorders including atherosclerosis, hypertension, cardiac remodeling, and heart failure; however, its role is not fully understood. Since an assortment of innate responsive cells, e.g., neutrophils and monocytes/macrophages, coordinate with adaptive immunity, e.g., T cells, dendritic cells, and B cells, the temporal response and descriptions pertinent to the cellular phenotype and inflammation processes, in general, need additional investigation, clarification, and consensus particularly in cardiovascular disease. This Perspectives article reviews the contributions of 15 articles (including 7 reviews) published in the

Indexed as

Adaptive ImmunityAnimalsCardiovascular DiseasesHomeostasisHumansImmunity, InnateInflammationadaptive immunityatherosclerosiseosinphiliahypertensionmyocardial infarction

Identifiers

PMID31702971
PMCPMC6960777
OpenAlexW2983916503

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.