Evidence map›Paper›PMID 31702944›Full record

ArticleJournal of global oncology2019

Dermatology-Driven Quality Improvement Interventions to Decrease Diagnostic Delays for Kaposi Sarcoma in Botswana.

Victoria L Williams, Mohan Narasimhamurthy, Olaf Rodriguez, Karen Mosojane, Thapelo Bale, Koorileng Kesalopa, Mukendi A Kayembe, Surbhi Grover

Open access · goldAbstract read
In one paragraph

Article in Journal of global oncology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.4field-weighted citation impact, top 33% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 8 citations in OpenAlex.

  1. Article
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  3. Review
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  5. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 5 institutions in 2 countries.

Victoria L WilliamsUniversity of Botswana, Gaborone, Botswana.
Mohan NarasimhamurthyUniversity of Botswana, Gaborone, Botswana.
Olaf RodriguezUniversity of Pennsylvania, Philadelphia, PA.
Karen MosojanePrincess Marina Hospital, Gaborone, Botswana.
Thapelo BaleNational Health Laboratory, Gaborone, Botswana.
Koorileng KesalopaNational Health Laboratory, Gaborone, Botswana.
Mukendi A KayembeUniversity of Botswana, Gaborone, Botswana.
Surbhi GroverUniversity of Botswana, Gaborone, Botswana.
Botswana Vaccine Institute (Botswana) · BWUniversity of Botswana · BWUniversity of Pennsylvania · USBotswana Harvard AIDS Institute Partnership · BWBotswana Open University · BW

Funding

Shared Resources CoreU54CA190158 · NCI · UNIVERSITY OF PENNSYLVANIA · PI ROBERTSON, ERLE S. · 2014 to 2023
$4.2M
Prognostic value of quantitative HPV viral load in determining cervical cancer treatment response and recurrenceK08CA230170 · NCI · UNIVERSITY OF PENNSYLVANIA · PI GROVER, SURBHI · 2019 to 2023
$1.4M
NCI NIH HHS K08 CA230170NCI NIH HHS U54 CA190158
6 · The paper itself

Abstract

purposeKaposi sarcoma (KS) is an HIV-associated skin cancer that is highly prevalent in Botswana and associated with significant morbidity and mortality. Histopathology-confirmed diagnosis is required for chemotherapeutic interventions in Botswana, which creates barriers to care because of limited biopsy and pathology services. We sought to understand the role a dermatology specialist can play in improving KS care through quality improvement (QI) initiatives to reduce histologic turnaround times (TATs) for KS.

methodsEmployment of a dermatology specialist within a public health care system that previously lacked a local dermatologist generated quality improvements in KS care. Retrospective review identified patients diagnosed with KS by skin biopsy in the predermatology QI interval (January 1, 2015, to December 31, 2015) versus the postdermatology QI interval (January 1, 2016, to November 31, 2017). Histology TATs and clinical characteristics were recorded. A

resultsA total of 192 cases of KS were diagnosed by skin biopsy. Nearly all (98.4%) were HIV-positive; and 52.8% of patients were male with a median age of 39 years. Median TAT in the postdermatology QI interval was 11 days (interquartile range, 12-23 days) compared with 32 days in the predermatology QI interval (interquartile range, 24-56 days;

conclusionDermatology-led QI initiatives to improve multispecialty care coordination can significantly decrease histology TATs for KS. The reduction of diagnostic delays is a key first step to decreasing the morbidity and mortality associated with this cancer in resource-limited settings.

Indexed as

AdultAgedBotswanaDermatologyFemaleHumansMaleMiddle AgedQuality ImprovementSarcoma, KaposiYoung Adult

Identifiers

PMID31702944
PMCPMC6882519
OpenAlexW2987073064

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.