Evidence map›Paper›PMID 31702926›Full record

ArticleLangmuir : the ACS journal of surfaces and colloids2019

Cholesterol Regulates the Incorporation and Catalytic Activity of Tissue-Nonspecific Alkaline Phosphatase in DPPC Monolayers.

R Derradi, M Bolean, A M S Simão, L Caseli, J L Millán, M Bottini, P Ciancaglini, A P Ramos

Open access · greenAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Langmuir : the ACS journal of surfaces and colloids, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
1.6field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 15 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 4 institutions in 3 countries.

R DerradiChemistry Department, Faculty of Philosophy, Sciences and Letters at Ribeirao Preto, Department of Chemistry , University of Sao Paulo , Avenida Bandeirantes, 3900, Monte Alegre , Ribeirao Preto , SP Brazil , 14040-901.
M BoleanChemistry Department, Faculty of Philosophy, Sciences and Letters at Ribeirao Preto, Department of Chemistry , University of Sao Paulo , Avenida Bandeirantes, 3900, Monte Alegre , Ribeirao Preto , SP Brazil , 14040-901.
A M S SimãoChemistry Department, Faculty of Philosophy, Sciences and Letters at Ribeirao Preto, Department of Chemistry , University of Sao Paulo , Avenida Bandeirantes, 3900, Monte Alegre , Ribeirao Preto , SP Brazil , 14040-901.
L CaseliInstitute of Environmental, Chemical and Pharmaceutical Sciences , Federal University of Sao Paulo , Rua Sao Nicolau, 210, Centro , Diadema , SP Brazil , 09913-030.
J L MillánSanford Burnham Prebys Medical Discovery Institute , La Jolla , California 92037 , United States.
M BottiniSanford Burnham Prebys Medical Discovery Institute , La Jolla , California 92037 , United States.ORCID 0000-0001-9237-8972
P CiancagliniChemistry Department, Faculty of Philosophy, Sciences and Letters at Ribeirao Preto, Department of Chemistry , University of Sao Paulo , Avenida Bandeirantes, 3900, Monte Alegre , Ribeirao Preto , SP Brazil , 14040-901.
A P RamosChemistry Department, Faculty of Philosophy, Sciences and Letters at Ribeirao Preto, Department of Chemistry , University of Sao Paulo , Avenida Bandeirantes, 3900, Monte Alegre , Ribeirao Preto , SP Brazil , 14040-901.ORCID 0000-0001-6200-8989
Universidade de São Paulo · BRSanford Burnham Prebys Medical Discovery Institute · USUniversidade Federal de São Paulo · BRUniversity of Rome Tor Vergata · IT

Funding

MOLECULAR PATHOGENESIS/TREATMENT OF HYPOPHOSPHATASIAR01DE012889 · NIDCR · SANFORD BURNHAM PREBYS MEDICAL DISCOVERY INSTITUTE · PI MILLAN, JOSE LUIS · 1999 to 2020
$9.2M
NIDCR NIH HHS R01 DE012889
6 · The paper itself

Abstract

Matrix vesicles (MVs) are a special class of extracellular vesicles that drive bone and dentin mineralization by providing the essential enzymes and ions for the nucleation and propagation of mineral crystals. Tissue-nonspecific alkaline phosphatase (TNAP) is an integral protein of MV membrane and participates in biomineralization by hydrolyzing extracellular pyrophosphate (PP

Indexed as

Membranes, Artificial1,2-DipalmitoylphosphatidylcholineAlkaline PhosphataseCatalysisCholesterolProtein Binding1,2-DipalmitoylphosphatidylcholineAlkaline PhosphataseCholesterolMembranes, Artificial

Identifiers

PMID31702926
PMCPMC7105399
OpenAlexW2983984116

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.