Evidence map›Paper›PMID 31702655›Full record

Trial reportMedicine2019

Effects of rhythmic auditory cueing on stepping in place in patients with Parkinson's disease.

Hsiu-Yun Chang, Ya-Yun Lee, Ruey-Meei Wu, Yea-Ru Yang, Jer-Junn Luh

Open access · goldAbstract readRandomized Controlled Trial
In one paragraph

Trial report in Medicine, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed, 2 pooled it
1.1field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 2 syntheses or guidelines pooled it, 15 citations in OpenAlex.

  1. Pooled it
  2. Guideline
  3. Review
  4. Article
  5. Review
  6. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 2 countries.

Hsiu-Yun ChangSchool and Graduate Institute of Physical Therapy, College of Medidine.
Ya-Yun LeeSchool and Graduate Institute of Physical Therapy, College of Medidine.
Ruey-Meei WuDepartment of Neurolyg, College of Medicine, National Taiwan University.
Yea-Ru YangDepartment of Physical Therapy, School and Graduate Institute of Physical Therapy, National Yang-Ming University.
Jer-Junn LuhSchool and Graduate Institute of Physical Therapy, College of Medidine.
National Taiwan University · TWNational Yang Ming Chiao Tung University · TW

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundStepping in place (SIP) is a useful locomotor training intervention. The purpose of this study was to investigate the effects of single auditory-cued SIP training on cortical excitability, rhythmic movements and walking ability in patients with Parkinson's disease(PD).

methodsCross-over randomized control trial. Each participant completed two interventions with at least one-week washout period in between: (1) SIP with concurrent auditory cues (AC condition) and (2) SIP without auditory cues (NC condition).

resultsIn the primary outcome, the cortical silent period (CSP) duration increased (P = .005), whereas short intracortical inhibition (SICI) decreased after training (P = .001). Freezers demonstrated enhanced inhibition in the resting motor threshold and CSP duration. SICI and intracortical facilitation were modulated in both groups under the AC condition. In the secondary outcomes, the stepping variability decreased significantly (AC: P = .033; NC: P = .009), whereas walking cadence increased after training (AC: P = .019; NC: P = .0023).

conclusionsAuditory-cued SIP training improved the lower-limb movement variability and modulated the cortical excitability in patients with PD. Freezers may benefit more from this training than nonfreezers.

Indexed as

CuesAcoustic StimulationAgedCross-Over StudiesEvoked Potentials, AuditoryGait Disorders, NeurologicHumansMiddle AgedParkinson DiseasePhysical Functional PerformancePhysical Therapy ModalitiesTranscranial Magnetic StimulationWalking

Identifiers

PMID31702655
PMCPMC6855520
OpenAlexW2883190684

What OpenQuestion holds

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LicenceCC BY-NC
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.